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Cat. No. Product Name Field of Application Chemical Structure
DC46329 Phoyunnanin E
Phoyunnanin E, isolated from Dendrobium venustum, possesses anti-migration activity. Phoyunnanin E can be used for the research of cancer.
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DC46328 NHS-MMAF
NHS-MMAF is a modified MMAF extracted from patent WO2012143499, intermediat 219. MMAF is a potent tubulin polymerization inhibitor and is used as a antitumor agent
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DC46327 Methyl 5-hydroxypyridine-2-carboxylate
Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro.
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DC46326 (±)-H3RESCA-TFP
(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine).
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DC46325 Diaplasinin
Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 295 nm. Antithrombotic efficacy.
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DC46324 Nelonicline citrate
Nelonicline (ABT-126) citrate is an orally active and selective α7 nicotinic receptor agonist with high affinity to α7 nAChRs in human brain (Ki=12.3 nM). Nelonicline citrate is used for the research of shizophrenia and Alzheimer's disease.
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DC46323 17β-Estradiol sulfate sodium
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid.
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DC46322 Xylopine
Xylopine is an aporphine alkaloid with cytotoxic activity on cancer cells. Xylopine induces oxidative stress, causes G2/M cell cycle arrest and apoptosis in cancer cells.
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DC46321 SiR-COOH
SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm).
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DC46320 HBC599
HBC599 is a HBC analog. HBC is nonfluorescent in solution, but emits strong fluorescence upon forming tight complex with Pepper RNA aptamer. HBC-Pepper complex can be used to visualize RNA dynamics in live cells.
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DC46319 PF-945863
PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains.
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DC46318 Goitrin
Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity.
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DC46317 3'-Hydroxyxanthyletin
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities.
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DC46316 1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone
1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone, as a colorless oil, is a quinolone alkaloid isolated from the fruit of Evodia rutaecarpa BENTHAM (Rutaceae).
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DC46315 trans,trans-2,4-Decadienal
trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid.
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DC46314 Notch 1 TFA
Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types.
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DC46313 Photo-lysine hydrochloride
Photo-lysine hydrochloride, a new lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications.
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DC46312 Adipokinetic Hormone (AKH) (24-32), locust TFA
Adipokinetic Hormone (AKH) (24-32), locust (TFA), isolated from locust corpora cardiaca, is a neurohormone that regulates lipid utilisation during flight.
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DC46311 TAT-cyclo-CLLFVY TFA
TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY TFA disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM.
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DC46310 Nefopam D3 hydrochloride
Nefopam D3 hydrochloride is the deuterium labeled Nefopam hydrochloride. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo.
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DC46308 Ipatasertib-NH2 dihydrochloride
Ipatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase.
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DC46307 Norgestimate D6
Norgestimate D6 is the deuterium labeled Norgestimate. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive.
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DC46306 Ganciclovir mono-O-acetate
Ganciclovir mono-O-acetate is a derivative of Ganciclovir. Ganciclovir, a nucleoside analogue, is an orally active antiviral agent with activity against CMV.
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DC46305 4-Hydroxymephenytoin D3
4-Hydroxymephenytoin D3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate.
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DC46304 Trimethylolpropane ethoxylate triacrylate
Trimethylolpropane ethoxylate triacrylate (ETPTA) is a plasticizer that can be used synthesize nanocomposites.
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DC46303 PFB-FDGlu
PFB-FDGlu is a selective lysosomal Glucocerebrosidase (GCase) substrate, which is metabolised by GCase to yield fluorescein. PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis.
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DC46302 Hexidium iodide
Hexidium iodide, a fluorescent nucleic binding acid stain (excitation/emission ~ 518/600 nm), permeants to mammalian cells and selectively stains almost all gram-positive bacteria. Hexidium iodide can bind to the DNA of all bacteria after permeabilization by EDTA.
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DC46301 Vitamin K1 D7
Vitamin K1 D7 (Phylloquinone D7) is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
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DC46300 IDH-C227
IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts.
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DC46298 SW157765
SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs.
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