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Cat. No. Product Name Field of Application Chemical Structure
DC44039 Hydroxy-PEG3-ethyl acetate
Hydroxy-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44038 Acryloyl-PEG4-OH
Acryloyl-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44037 NH2-PEG2-methyl acetate
NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44036 4-Methylcinnamic acid
4-Methylcinnamic acid, a Cinnamic acid analog, can be used as a intervention catalyst for overcoming antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents.
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DC44035 (-)-Bornyl acetate
(-)-Bornyl acetate (L-(-)-Bornyl acetate), isolated from hyssop oil, is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate possesses antifungal activity.
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DC44034 Benzyl-PEG1-propanol
Benzyl-PEG1-propanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44033 Benzyl-PEG2-MS
Benzyl-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44032 Azido-PEG4-THP
Azido-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44031 Benzyl-PEG2-CH2COOH
Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44030 L-Uridine
L-Uridine, isolated from the Polyporaceae fungus Poria cocos (Schw.), is an enantiomer of the normal RNA constituent D-uridine. L-uridine acts as a phosphate acceptor for nucleoside phosphotransferases.
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DC44029 TEI-9648
TEI-9648, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research.
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DC44028 m-PEG1000-CH2COOH
m-PEG1000-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44027 NH2-PEG-Strt (MW 3000)
NH2-PEG-Strt (MW 3000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC44026 NH2-PEG-Strt (MW 10000)
NH2-PEG-Strt (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC44025 m-PEG750-Br
m-PEG750-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44024 Boc-NH-PEG-Thiol (MW 10000)
Boc-NH-PEG-Thiol (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC44023 Ethoxylated hydrogenated castor oil
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo.
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DC44022 Hydroxy-PEG4-methyl acetate
Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44021 Z-LE(OMe)TD(OMe)-FMK
Z-LE(OMe)TD(OMe)-FMK is a selective caspase-8 inhibitor. Z-LE(OMe)TD(OMe)-FMK can inhibit cell apoptosis.
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DC44020 PIM1-IN-1
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity.
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DC44019 BNC375
BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM. BNC375 exhibits good CNS-drug like properties and clinical candidate potential. .
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DC44018 Naph-EA-mal
Naph-EA-mal (Thiol-green 1) is a rapid detect and ultrafast turn-on thiol fluorescence probe for protein labeling and bioimaging. Naph-EA-mal (Thiol-green 1) can be used to detect thiols in living cells, label the protein thiols, quantify the concentration of total thiols in cell lysate, and determine the reversible protein thiols oxidation in fixed cells. Ex: 488 nM; Em: 540 nM.
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DC44017 GSK-3/CDK5/CDK2-IN-1
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases.
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DC44016 Benzyl-PEG2-acid
Benzyl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44015 (-)-Anomalin
(-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of S. resinosum.
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DC44014 H2N-PEG2-CH2COOtBu
H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44012 4'-Hydroxy-2'-methylacetophenone
4'-Hydroxy-2'-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4'-Hydroxy-2'-methylacetophenone has ciliate toxicity. 4'-Hydroxy-2'-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM.
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DC44011 Propenyl-PEG3-Propenyl
Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44010 BOC-NH-PEG2-propene
BOC-NH-PEG2-propene is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44009 FNDR-20123 free base
FNDR-20123 free base is an orally active, safe and a first-in-class anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 free base exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50=41 nM) and sexual blood stage (IC50=190 nM for male gametocytes). FNDR-20123 free base inhibits HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 (IC50=25, 29, 2, 11, and 282 nM, respectively) and inhibits Class III HDAC isoforms at nanomolar concentrations.
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