CGP60474|cas 164658-13-3|DC Chemicals|Price|Buy

Cas No.:	164658-13-3
Chemical Name:	CGP60474
Synonyms:	1-Propanol,3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-;CGP60474;3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol;1-Propanol, 3-((4-(2-((3-chlorophenyl)amino)-4-pyrimidinyl)-2-pyridinyl)amino)-;AC1LD8S6;CGP-60474;GNF-Pf-88;UNII-16IP6G5MLC;3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol;REGID_for_CID_644215;HMS3265F05;DTXSID00167788;HMS3265E06;SMR000463552;J-511450;A910858;CHEMBL300389;HY-11009;NCGC00346940-02;3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol;CGP 60474;EX-A4558;16IP6G5MLC;MLS000911536;HMS2043A05;8II;D97331;HMS2218H05;NCGC00346940-01;SCHEMBL1574530;BCP27893;3-((4-(2-(3-Chlorophenylamino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol;1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]- (9CI);3-[[4-[2-[(3-chlorophenyl)amino]pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol;AS-76789;Q27163218;3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]-2-pyridyl]amino]propan-1-ol;BDBM65549;cid_644215;AKOS027470190;VCC459317;HMS3265E05;MLS003105942;HMS3340I17;HMS3265F06;CHEBI:91339;3-({4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl}amino)propan-1-ol;164658-13-3;3-((4-(2-((3-Chlorophenyl)amino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol;1-propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-;DA-62247;DTXCID8090279;3-[(4-{2-[(3-CHLOROPHENYL)AMINO]PYRIMIDIN-4-YL}PYRIDIN-2-YL)AMINO]PROPAN-1-OL
SMILES:	ClC1=CC(NC2=NC=CC(C3=CC=NC(NCCCO)=C3)=N2)=CC=C1
Formula:	C₁₈H₁₈N₅OCl
M.Wt:	355.82142
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

Description:

CGP60474 is a promising inhibitor of PKC with a high degree of selectivity versus other serine/threonine and tyrosine kinases and show competitive kinetics relative to ATP.For the detailed information of CGP60474, the solubility of CGP60474 in water, the

COA

MSDS

Cat. No.	Product name	Field of application
DC50088	H-7 inhibitor	H-7 is a specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
DC50087	1,2-Dimyristoyl-sn-glycerol	1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol and a weak second messenger for the activation of PKC.
DC46451	CC-90005	CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by IL-2 expression.
DC40357	PKC-iota inhibitor 1	PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ?) inhibitor with an IC50 value of 0.34 μM.
DC40325	ζ-Stat trisodium	ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM. ζ-Stat trisodium can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro.
DC28545	N-Desmethyltamoxifen hydrochloride	N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent re
DC28544	N-Desmethyltamoxifen	N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
DC28223	Bisindolylmaleimide IV	Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM.
DC7382	CGP60474	CGP60474 is a potent inhibitor of cyclin-dependent kinase (CDK).
DC7421	GO 6976	Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.