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CC-90005

  Cat. No.:  DC46451   Featured
Chemical Structure
1799574-70-1
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More than 5000 active chemicals with high quality for research!
Field of application
CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by IL-2 expression.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1799574-70-1
Chemical Name: 2-(((4-(2,2-Difluoropropoxyl)pyrimidin-5-yl)methyl)amino)-4-(((1R,4S)-4-hydroxy-3,3-dimethylcyclohexyl)amino)pyrimidine-5-carbonitrile
Synonyms: GEZ43HM6NW;GTPL11659;compound 57 [PMID: 34355886];2-(((4-(2,2-difluoropropoxy)pyrimidin-5-yl)methyl)amino)-4-(((1R,4S)-4-hydroxy-3,3-dimethylcyclohexyl)amino)pyrimidine-5-carbonitrile;2-(((4-(2,2-difluoropropoxyl)pyrimidin-5-yl)methyl)amino)-4-(((1R,4S)-4-hydroxy-3,3-dimethylcyclohexyl)amino)pyrimidine-5-carbonitrile;2-[[4-(2,2-difluoropropoxy)pyrimidin-5-yl]methylamino]-4-[[(1R,4S)-4-hydroxy-3,3-dimethylcyclohexyl]amino]pyrimidine-5-carbonit
SMILES: FC(C([H])([H])[H])(C([H])([H])OC1C(=C([H])N=C([H])N=1)C([H])([H])N([H])C1=NC([H])=C(C#N)C(=N1)N([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])O[H])F
Formula: C21H27F2N7O2
M.Wt: 447.4816
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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