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CP-447697

  Cat. No.:  DC72349   Featured
Chemical Structure
1092847-21-6
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More than 5000 active chemicals with high quality for research!
Field of application
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1092847-21-6
Chemical Name: CP-447697
Synonyms: 1-Piperidinecarboxamide, 4-[(benzo[b]thien-3-ylcarbonyl)[2-(4-chlorophenyl)ethyl]amino]-N-(2,4-difluorophenyl)-;CP-447697
SMILES: N1(C(NC2=CC=C(F)C=C2F)=O)CCC(N(C(C2=CSC3=CC=CC=C32)=O)CCC2=CC=C(Cl)C=C2)CC1
Formula: C29H26ClF2N3O2S
M.Wt: 554.05
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36800_DC72349_1092847-21-6
COA
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Cat. No. Product name Field of application
DC72349 CP-447697 CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
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DC28985 (Z)-Leukadherin-1 (Z)-Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z)-Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses.
DC11082 Danicopan (ACH-4471) Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.
DC11688 Avacopan Avacopan is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.
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