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(Z)-Leukadherin-1

  Cat. No.:  DC28985   Featured
Chemical Structure
2055362-72-4
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More than 5000 active chemicals with high quality for research!
Field of application
(Z)-Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z)-Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2055362-72-4
Chemical Name: (Z)-Leukadherin-1
Synonyms: Leukadherin-1;Leukadherin 1;LA1;BDBM8427;C22H26Cl2N2O11;AOB4116;SYN5137;BCP18444;s8306;STL372026;4-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid;(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid;4-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene];ADH-503 free base;(Z)-Leukadherin-1;NCGC00263554-08;EX-A2398;AC-33019;AKOS024458420;AG-690/12767735;344897-95-6;G60933;Leukadherin-1?;DA-74970;4-(5-{[(5Z)-3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid;BIM-0028118.P001;CCG-268900;4-{5-[(Z)-(3-benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid;4-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid;AB00093225-01;HF23I3UYO2;SCHEMBL18301010;GB-1275 free acid;Benzoic acid, 4-(5-((Z)-(4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene)methyl)-2-furanyl)-;UNII-HF23I3UYO2;4-{5-[(3-benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}benzoic acid;DA-48916;AS-16501;HY-15701;SCHEMBL46211;(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoicacid;C74771;ADH503 free acid;CS-5911;2055362-72-4
SMILES: S1C(N(C(/C/1=C/C1=CC=C(C2C=CC(C(=O)O)=CC=2)O1)=O)CC1C=CC=CC=1)=S
Formula: C22H15NO4S2
M.Wt: 421.48880314827
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
TITLE DOWNLOAD
MSDS_13036_DC28985_2055362-72-4
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
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DC44151 Complement factor D-IN-2 Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases.
DC28985 (Z)-Leukadherin-1 (Z)-Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z)-Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses.
DC11082 Danicopan (ACH-4471) Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.
DC11688 Avacopan Avacopan is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.
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