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Amyloids

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Cat. No. Product Name Field of Application Chemical Structure
DC44795 β-Amyloid (22-40)
β-Amyloid (22-40) is a peptide fragment of β-Amyloid.
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DC44794 β-Amyloid (11-22)
β-Amyloid (11-22) is a peptide fragment of β-Amyloid.
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DC41886 AC 253
AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.
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DC41885 Amyloid β-Peptide (1-37) (human)
Amyloid β-Peptide (1-37) (human) is an amyloid β-protein fragment cleaved from amyloid precursor protein (APP).
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DC41837 β-Amyloid (22-35) (TFA)
β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA, the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 TFA forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution).
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DC41816 Amyloid β-Peptide(1-43)(human) TFA
Amyloid β-Peptide(1-43) human TFA, the Human β-amyloid peptide, is minor component of neuritic plaques found in brains of patients with Alzheimer's disease.
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DC41815 Amyloid β-Peptide(1-43)(human)
Amyloid β-Peptide(1-43) human, the Human β-amyloid peptide, is minor component of neuritic plaques found in brains of patients with Alzheimer's disease.
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DC41547 LPYFD-NH2 TFA
LPYFD-NH2 TFA, a pentapeptide, exerts some inhibitory effect on the aggregation of Aβ(1-42). LPYFD-NH2 TFA can be used for the research of Alzheimer’s disease.
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DC41546 LPYFD-NH2
LPYFD-NH2, a pentapeptide, exerts some inhibitory effect on the aggregation of Aβ(1-42). LPYFD-NH2 can be used for the research of Alzheimer’s disease.
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DC41528 β-Amyloid (1-40) (TFA)
β-Amyloid (1-40) TFA is a primary protein in plaques found in the brains of patients with Alzheimer's disease.
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DC42447 gamma-Secretase Modulators
gamma-Secretase Modulators (Amyloid-β production) is a Amyloid-β production.
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DC42446 TML-6
TML-6 inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 upregulates Apo E and suppresses NF-κB, mTOR. TML-6 increases the activity of the anti-oxidative Nrf2 gene. TML-6, an orally active curcumin derivative, has the potential for Alzheimer’s disease (AD) research.
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DC11091 TRX-0237
TRX-0237 Methylate (Hydromethylthionine, Methylene blue) is a Tau aggregation inhibitor (TAI) with Ki of 0.12 uM for intracellular TAI activity.
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