Brain penetrant, selective and high affinity OX1R antagonist

Novel anthelmintic agent

Novel anthelmintic agent, immobilising whipworm and reducing the ability of embryonated T. muris eggs to establish infection in the mouse host in vivo

First-in-class small molecule potentiator of cancer virotherapy, significantly enhancing virus replication-associated luciferase expression specifically in the tumor

Narural broad anticancer agent, upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway

Ovalbumin fragment peptide for study class II MHC-peptide binding and T-cell activation, binding to I-A(d) MHC class II protein, encompassing an allergenic and antigenic epitope of the ovalbumin protein

Ovalbumin fragment peptide as a class I (Kb)-restricted peptide epitope, triggering T cell activation in immunology studies

High affinity and human/rat species-selective histamine H3 receptor antagonist

Natural inhibitor of the Na+/K+-ATPase sodium-potassium ion pump

Novel potent inhibitor of the natural function of FDX1, promoting a unique form of copper-dependent cell death

Novel AMPK activator, inhibiting mTOR signaling and autophagy stimulation, activating mutations in RAS or BRAF

Novel Inhibitor of Migration and Invasion of Osteosarcoma Cells Mediated by p53, Regulating EMT-Related Genes

Novel Inhibitor of Migration and Invasion of Osteosarcoma Cells Mediated by p53, Regulating EMT-Related Genes

Soluble secreted member of the tumor necrosis factor receptor superfamily, inhibiting osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, leading to excess accumulation of bone and cartilage

Novel inhibitor of osteoclast differentiation through regulating MAPKs and Akt signaling pathways

Inhibitor of the glycan-processing enzyme endoplasmic-reticular glucosidase

Novel cGMP phosphodiesterase (cGMP-PDE) inhibitor

Novel potent, orally efficacious, dual inhibitor of cMET and RON kinases

Inhibitor of the influenza neuramidase enzyme, blocking neuraminidases on the surfaces of influenza viruses, interfering with host cell release of complete viral particles

Second-generation taxane derivative with potential antineoplastic activity, binding to and stabilizing tubulin molecules, inhibiting cell division and cellular proliferation

Peripheral weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist, preventing from being absorbed and entering the central nervous system

Inhibitor of an enzyme responsible for the multidrug resistance phenotype in the yeast Saccharomyces cerevisiae.

Novel potent dual orexin 1/2 receptor (OX1/2R) antagonist for the treatment of insomnia

Novel sodium/calcium exchanger (NCX) inhibitor

Lipoglycopeptide Antibacterial, acting as a inhibitor of Cytochrome P450 2C19/2C9, and a inducer of Cytochrome P450 3A4/2D6

Selective p38alpha and p38beta kinase inhibitor

CB1 allosteric modulator

Negative allosteric modulator at the CB1 receptor

Novel mixed κ/μ receptor antagonist. having therapeutic potential for the treatment of depression and other stress-induced conditions

Collagen immunostain