[SER140]-PLP(139-151)|CAS 122018-58-0|DC Chemicals

Cas No.:	122018-58-0
Chemical Name:	Proteolipid protein (139-151)
Synonyms:	L-Phenylalanine,L-histidyl-L-seryl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-a-aspartyl-L-lysyl-;(SER140)-LIPOPHILIN (139-151) (DEPALMITOYLATED) (HUMAN, BOVINE, DOG, MOUSE, RAT);(Ser¹⁴⁰)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat);HSLGKWLGHPDKF;L-Phenylalanine,L-histidyl-L-seryl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histid...;L-Phenylalanine,L-histidyl-L-seryl-L-leucylglycyl-L-lysyl-L-tryptophyl-L-leucylglycyl-L-histidyl-L-prolyl-L-a-aspartyl-L-lysy;PLP (139-151);139-151 amino acid peptide of proteolipid protein;139-151 PLP;H2N-HSLGKWLGHPDKF-OH;H-HSLGKWLGHPDKF-OH;HIS-SER-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE;HIS-SER-LEU-GLY-LYS-TRP-LEU-GLY-HLS-PRO-ASP-LYS-PHE;PLP 139-151;PROTEOLIPID PROTEIN;PLP (HUMAN, BOVINE, DOG, MOUSE, RAT);MYELIN PROTEOLIPID PROTEIN (139-151);MYELIN PROTEOLIPID PROTEIN FRAGMENT (139-151);[Ser140] Myelin Proteolipid Protein (139-151);myelin PLP139-151;myelin PLP139-151\|PLP (139-151);Proteolipid protein (139-151)
SMILES:	O=C([C@]([H])(C([H])([H])C1=C([H])N=C([H])N1[H])N([H])C(C([H])([H])N([H])C([C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([C@]([H])(C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])N([H])C(C([H])([H])N([H])C([C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([C@]([H])(C([H])([H])O[H])N([H])C([C@]([H])(C([H])([H])C1=C([H])N=C([H])N1[H])N([H])[H])=O)=O)=O)=O)=O)=O)=O)=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])([H])C(=O)O[H])=O
Formula:	C₇₂H₁₀₄N₂₀O₁₇
M.Wt:	1521.7200
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	PLP(139-151) is a fragment of myelin proteolipid protein, induce experimental autoimmune encephalomyelitis (EAE).
In Vitro:	The residues 144 and 147 of PLP(139-151) are recognized by T cell receptor (TCR) during the formation of trimolecular complex with peptide-antigen and major histocompability complex[1].
References:	[1]. Kordopati GG, et al. Biologically relevant conformational features of linear and cyclic proteolipid protein (PLP) peptide analogues obtained by high-resolution nuclear magnetic resonance and molecular dynamics. J Comput Aided Mol Des. 2017 Jul 29.

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