Novel peptide STAT5 inhibitor, blocking IL-2/sIL-2Rα signaling and inhibiting T reg cell development

Novel ultrapotent and selective inhibitor of of human β-Factor XIIa

Novel Potent and Specific Target Of Rapamycin Complex 2 (TORC2) Inhibitor

Novel Hedgehog pathway inhibitor, revealing the receptor GPR39

Novel inhibitor of

Novel Epigenetic Inhibitor Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma

First-in-class dual PDE5 and HDAC6-selective inhibitor

Novel Matrix Metalloproteinase Inhibitor As a Potent Antihemorrhagic Agent

Novel selective agonist of cannabinoid CB2 receptors

Novel potent and selective dual inhibitor of c-Met and ALK, potently abrogating hepatocyte growth factor (HGF)-induced c-Met phosphorylation and cell migration, phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells

Novel inhibitor of

Novel chromophore-linked metallo-β-lactamase (MBL) substrate as potential inhibitor against a panel of clinically relevant MBLs

Precursor for tumor selective PET imaging (124I-CLR1404) or therapeutic radiation (131I-CLR1404)

Full agonist of GABAA receptors, acting as anxiolytic, sedative, hypnotic, amnesic, anticonvulsant and muscle relaxant agent

Long-acting benzodiazepine, producing the active metabolite desmethyl-diazepam, which is a partial agonist of the GABAA receptor

Herbicide safener that is added to various herbicide formulations to reduce crop damage

Hypolipaemic agent, reducing hypertriglyceridemia and hypercholesterolemia

Corticosteroid Hormone Receptor Agonist

Novel inhibitor of the human enzyme dimethylarginine dimethylaminohydrolase-1 (DDAH-1)

Potent and selective CLK1 and CLK2 inhibitor

Potent CLK1 and CLK2 inhibitor, also inhibiting SRPK1 and SRPK2

Prostaglandin I2 analogue, dose-dependently inhibiting human and rabbit platelet aggregation and human platelet adhesion in vitro

Novel hypoxia-inducible factor (HIF)-1 inhibitor

Antibiotic, acting as a mechanism-based β-lactamase inhibitor

Novel two-photon polarity-sensitive lipid membrane probe

Natural modulator of voltage-gated sodium (NaV) channels

The most potent clathrin terminal domain-amphiphysin inhibitor reported to date

Novel protein tyrosine phosphatase-1B (PTP1B) inhibitor, neutralizing the toxicity of α-hemolysin, inhibiting β-secretase 1 (BACE1)-mediated insulin receptor cleavage

Inhibitor of respiratory syncytial virus (RSV)

Inhibitor of H5N1 avian influenza A virus infection