Natural inhibitor of protein tyrosine phosphatase 1B (PTP1B)

Novel fluorogenic dye for Live-Cell Fluorescence Microscopy

Fluorogenic dye for Live-Cell Fluorescence Microscopy

Novel Fluorescent, Highly Affine Histamine H3 Receptor Ligand

Novel covalent substrate-competitive inactivator of AKT kinase

Inhibitor of topoisomerase I/II, inducing DNA cross-linking and significantly suppressing the growth of various NSCLC cell lines with or without mutations in epidermal growth factor receptor (EGFR)

Selective delta 1 opioid receptor antagonist

Solvatochromic Nile Red Probe with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

Novel CD4 mimic, inhibiting HIV-1 entry into target cells with both significantly higher potency and neutralization breadth than previous congeners, while maintaining high selectivity for the target virus

Potent long-acting H2-receptor antagonist

Novel fluorescent activity-based probe (ABP), being intrinsically dark and only emitting fluorescence after reaction with the target protease, are ideally suited for imaging techniques such as small animal noninvasive fluorescence imaging and live cell fl

G-quadruplex ligand, decreasing oncogene expression

Novel pan-genotype inhibitor of HCV NS5B polymerase via binding to the primer grip site

Novel γ-secretase modulator

Novel S1P1 receptor modulator

Novel GPR119 agonist

Selective RARγ agonist

Novel Agonist of Sphingosine-1-Phosphate (S1P1)

Potent and selective GPR119 agonist

Potent alpha7 Nicotinic receptor partial agonist, improving cognition in preclinical rodent model

Novel inhibitor of the influenza nucleoprotein (INF-NP)

Novel potent and selective P2Y1 purinergic receptor antagonist.

Potent, Orally Bioavailable, Metabolically Stable Thumb Site 1 Inhibitor of the Hepatitis C Virus NS5B RNA-Dependent, RNA Polymerase

Novel potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1)

Novel potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1)

Novel Novel γ-secretase modulator, decreasing Aß1-40 and Aß1-42 and increasing Aß1-37 and Aß1-38 in rat brain modulator, decreasing Aß1-40 and Aß1-42 and increasing Aß1-37 and Aß1-38 in rat brain

Novel potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1)

Novel Inhibitor of human immunodeficiency virus type 1 (HIV-1) attachment

Novel, potent, exceptionally selective inhibitor of TNF-α Converting Enzyme (TACE)

Potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor