Novel inhibitor of HCV NS3-NS4A Serine Proteinase

Inhibitor of T-type voltage-gated calcium channels (Cav3), inhibiting isoforms Cav3.1, Cav3.2, and Cav3.3, decreasing nifedipine-resistant phenylephrine-induced vasoconstriction via Cav3.2 blockade

Bulding Block

Useful pharmaceutical building block

Useful pharmaceutical building block

Inhibitor of Androgen_receptor>androgen receptor (AR) transcriptional activity, more effective than resveratrol in inhibiting AKT>Akt phosphorylation

Novel anti-austerity agent, inducing PANC-1 human pancreatic cancer cell death under nutrition starvation via inhibition of Akt/mTOR pathway

Novel ligand for LTA4H, dose responsively reducing LTB4 production in human neutrophils

Novel Potent and Selective Kappa Opioid Receptor Antagonist

Dopamine reuptake inhibitor

Potent agonist of tropomyosin-receptor-kinase B (TrkB) receptor, possessing robust anti-apoptotic activity, promoting neurogenesis, and exhibiting potent antidepressant effect

Potent Antifungal Inhibitor of Chitin Synthesis

Novel selective ligand of the Transport Inhibitor Resistant 1 (TIR1)

Prodrug of 7-Cl-kynurenic acid (7-Cl-KYNA), a potent, selective antagonist of the NMDA/glycine receptor

Novel Transthyretin (TTR) Amyloidogenesis Inhibitor, stabilizing the TTR tetramer by binding to the allosteric sites on the molecular surface of the TTR tetramer

Ca ionophore. potentiating responses to NMDA, but not quisqualate

Photoreactive L-phenylalanine derivative, being as a photo cross-linking probe to incorporate into proteins, including ion channels, transporters and GPCRs

Clickable fluorescent probe, enabling dynamic imaging of cell surface and intracellular fucosylation of glycoproteins and glycolipids.

Mutually Orthogonal Bioorthogonal Amino Acid, Enabling Efficient Protein Dual-Labeling in Cells

Natural selective estrogen receptor modulator, showing higher binding affinity to ER-β than ER-α with both estrogenic and antiestrogenic effects depending on the E2 concentration

Selectiveγ‑Aminobutyric Acid(C) (GABAC) Antagonist

Selectiveγ

Selectiveγ

Natural inhibitor of the autophagy pathway, enhancing immune function, suppressing MAPK and NFκB, showing anti-inflammatory, hypoglycemic, vasorelaxative, and antiproliferative activities

Antioxidant, significantly increased gene expression of the anti-aging factor, SIRT1, stimulating the expression of skin growth factor and inhibiting pro-inflammatory genes

5HT(1B/1D) receptor partial agonist, inhibiting electrically induced plasma extravasation, blocking neurogenic plasma protein extravasation, inhibiting release of calcitonin gene-related peptide

Novel potent and selective triple reuptake inhibitor (TRI)

Potent antagonist of the Pseudomonas aeruginosa Transcriptional Regulator PqsR

Useful building block and intermediate

Natural inhibitor of RORγt, ittenuating Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation