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Cat. No. Product Name Field of Application Chemical Structure
DC31804 Pentoxifylline
Pentoxifylline is a drug used to treat muscle pain in people with peripheral artery disease. Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. It is being investigated for treatment of Alzheimer's disease. It is generic and sold under many brand names worldwide.
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DC34491 Halofuginone HBr
Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.
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DC37832 Methyl leucylleucinate hydrochloride
Methyl leucylleucinate HCl is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells.1,2 It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells.2 Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.2
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DC36314 Urapidil HCl
Urapidil HCl is an antagonist of α1-adrenergic receptors (α1-ARs) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. Urapidil HCl inhibits cAMP accumulation induced by forskolin. It is also a β1-AR antagonist that inhibits the positive chronotropic response induced by isoproterenol. Urapidil HCl lowers mean arterial pressure (MAP) in anesthetized cats, an effect that is reduced by central administration of the 5-HT1A receptor antagonist spiroxatrine.
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DC37725 (-)-Carvone
(-)-Carvone is one of the key constituents of spearmint (Mentha spicata) oil. Studies indicate that it is a potent feeding-deterrent to stored product beetles
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DC38050 Lobenzarit sodium
Lobenzarit sodium is an antirheumatic agent.
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DC37885 Captopril disulfide
Captopril disulfide is a metabolite of Captopril. A new antihypertensive agent.
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DC33822 Iodoacetic acid
Iodoacetic acid is a reagent for the modification of sulfhydryl groups. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing.
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DC36496 Bauerenol
Bauerenol is a triterpenoid from Indian Suregada angustifolia, is isolated from the stem bark of Acronychia pedunculata., Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. Bauerenol is an Antitrypanosomal Agent.
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DC36737 Bemegride
Bemegride is a central nervous system stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
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DC37505 Ibuprofen piconol
Ibuprofen piconol is a Pyridyl ester of ibuprofen.
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DC36879 Cefuroxime axetil
Cefuroxime axetil is a second generation cephalosporin antibiotic with a broad spectrum activity against Gram positive and Gram negative bacteria.
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DC36731 Oxprenolol hydrochloride
Oxprenolol hydrochloride is a non-selective beta-adrenergic blocking agent that also possesses intrinsic sympathomimetic activity (ISA) and membrane stabilizing effects. Oxprenolol hydrochloride undergoes first pass metabolism with only 30% of an oral dose reaching the systemic circulation. The drug is approximately 80% protein bound and is eliminated primarily by glucuronidation in the liver. Less than 4% of oxprenolol hydrochloride is excreted unchanged in the urine. Oxprenolol hydrochloride may reduce the heart rate and prolong the effective and functional atrioventricular nodal refractory period. It appears to be comparable to other beta blockers in the treatment of hypertension and angina pectoris with no additional adverse reactions.
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DC37138 2-Hydroxychalcone
2-Hydroxychalcone can be used as antiparasitic hit compounds when Methoxylated.
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DC36118 Ageratochromene
Precocene II is an antiallotropin compound capable of inhibiting juvenile hormone biosynthesis. Precocene II has antibacterial, antifungal, insecticidal, and antioxidant activities.
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DC34516 TD3
TD-3 is an inhibitor of the salt-bridge formation between β-Asp94 and β-His146 hemoglobin (Hb), binding to Hb β-Cys93.
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DC36230 3H-Amt
Aminomethyltrioxsalen is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.
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DC36130 Ankerbin
Cloxacillin Sodium is a semi-synthetic antibiotic that is a chlorinated derivative of Oxacillin. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase.
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DC37351 Bis(2-ethylhexyl) terephthalate
Bis(2-ethylhexyl) terephthalate is a biochemical.
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DC35164 t-Boc-N-Amido-PEG3-azide
t-Boc-N-Amido-PEG3-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC36220 AI3-51572
ATMP, or aminotris(methylenephosphonic acid), is a phosphonic acid with chelating properties. It is an antiscalant.
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DC37346 Tetrine
Edetate Sodium is a Chelating Agent.
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DC34387 Paroxetine maleate
Paroxetine maleate is a selective serotonin reuptake inhibitor and an antidepressant.
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DC34246 Amodiaquin dihydrochloride
Amodiaquin dihydrochloride is an inhibitor of the Ebola virus. It acts by targeting the viral protein 35 (VP35).
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DC37742 Kassinin
Kassinin is a Dodecapeptide tachykinin found in the central nervous system of the amphibian Kassina senegalensis. It is similar in structure and action to other tachykinins, but is especially effective in contracting smooth muscle tissue and stimulating the micturition reflex.
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DC37462 639-14-5
Gypsogenin is a naturally occuring biochemical which exhibits anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.
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DC37259 Octadecanonitrile
Octadecanonitrile is a biochemical.
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DC37458 Dihydroxyphenylalanine
Dihydroxyphenylalanine is a beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific
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DC37701 Carbocysteine
Carbocysteine is a compound formed when iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expectorant action.
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DC36487 Cyclosporin B
Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts.
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