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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC21353 | MSN-125 |
MSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM.
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| DC21352 | MSC 1094308 |
MSC1094308 (MSC 1094308) is a reversible, allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B with IC50 of 7.2 and 0.71 uM, respectively.
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| DC23316 | MS7972 |
MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association.
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| DC21350 | MS4077 |
MS4077 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=3 nM).
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| DC21349 | MS-377 |
MS-377 is a potent, selective sigma-1 receptor ligand with Kd of 15.2 nM, showed anti-phencyclidine (PCP), anti-dopaminergic and anti-serotonergic activities.
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| DC21346 | MS012 |
MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..
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| DC23898 | MRT-83 hydrochloride |
MRT-83 hydrochloride is a potent Smoothened antagonist that blocks Hedgehog (Hh) signaling in various assays with IC50 of 10 nM.
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| DC21344 | MRT 199665 |
MRT 199665 is a potent salt-inducible kinases (SIKs) inhibitor with IC50 of 110, 12, 43 nM for SIK1,2,3 respectively.
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| DC22165 | MRS4478 |
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors..
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| DC22164 | MRS4458 |
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors..
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| DC12260 | MRS1177 |
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
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| DC23740 | MRS 2485 |
MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..
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| DC23733 | MRS 2481 |
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.
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| DC23471 | MRS 2179 tetrasodium |
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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| DC23483 | MRS 2179 |
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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| DC23711 | MRL20 |
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM.
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| DC21343 | MRL-1237 |
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
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| DC21923 | MRK-A |
MRK-A is a potent, highly selective, brain penetrant inhibitor of mutant IDH1 with IC50 of 5 nM, displays a 10,000-fold mutant to wildtype selectivity ratio.
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| DC23616 | MRK-696 |
MRK-696 is a non-selective benzodiazepine receptor partial agonist..
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| DC23655 | MRK-623 |
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist..
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| DC23877 | MRK-560 |
MRK-560 is a potent, brain-penetrant and orally bioavailable γ-secretase inhibitor that inhibits proteolytic cleavage of APP over the Notch pathway.
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| DC20465 | mPGES1-IN-17d |
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM.
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| DC20464 | mPGES1-IN-16 |
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM.
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| DC22554 | MP-A08 |
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1).
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| DCAPI1572 | Moxonidine hydrochloride |
Moxonidine hydrochloride
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| DCAPI1331 | Moxonidine |
Moxonidine
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| DC12485 | Mosedipimod |
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro.
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| DC8931 | Mosapride |
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
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| DC20042 | Monooctyl succinate |
Monooctyl succinate is a monoester, which can be used as a surfactants and a potential fragrance releaser.
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| DCAPI1006 | Monobenzone (Benoquin) |
Monobenzone (Benoquin)
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