Cas No.: | 101204-49-3 |
Chemical Name: | [2-[(hydroxy-oxidophosphoryl)oxymethyl]-5-(6-methylaminopurin-9-yl)oxolan-3-yl] hydrogen phosphate |
Synonyms: | MRS2179 |
SMILES: | N.O.CNC1N=CN=C2N([C@H]3C[C@H](OP(=O)(O)O)[C@@H](COP(=O)(O)O)O3)C=NC=12 |
Formula: | C11H17N5O9P22- |
M.Wt: | 425.2 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM; displays no appreciable activity at P2Y2, P2Y4, or P2Y6 receptors (>30 uM); inhibits ADP-induced platelet shape change, aggregation and Ca2+ rise but has no effect on ADP-induced inhibition of adenylyl cyclase; decreases platelet count in mice. |