3-Ethoxy-5,6-dibromosalicylaldehyde is a potent and selective inhibitor of IRE1 endoribonuclease with IC50 of 0.12 uM.

3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.

3-Cyanochromone is a potent gram-negative bacteria WcbL protein inhibitor with IC50 of 28 uM in a competitive enzyme-inhibition model, shows inhibition constants Ki of 10 uM..

3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia.

3-Acetylaconitine, aconitine, and deoxyaconitine are main toxic components of the roots of Aconitum pendulum.

3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities.

2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).

2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis.

2-mercaptoethane sulfonate (Mesna), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide.

2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM.

2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine.

22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..

20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein, binds at a site distinct from the canonical cyclopamine binding site.

2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfideintercalating cross-linking reagent.

1α,25-Dihydroxyvitamin D2 is an active metabolite of vitamin D. It is known that 1α,25-Dihydroxyvitamin D2 can be detected in human serum using high-performance liquid chromatography and ultraviolet detection. Vitamin D2, known as ergocalciferol, is a fat

1E7-03 is a small molecule targeting the RVxF interacting site on PP1, inhibits HIV-1, Ebolavirus (EBOV), and Venezuelan equine encephalitis virus (VEEV, EC50=0.6 uM).

1835F03 is a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus, inhibits the growth of a panel of S aureus strains (MIC=1-3 ug/mL), including clinical MRSA isolates..

10-NCP (10-DEBC) is a potent neuronal autophagy inducer and increases TDP43 clearance, a reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 uM).

103D5R is a small-molecule inhibitor of HIF-1α that displays an EC50 of 35 uM against hypoxia-induced alkaline phosphatase enzymatic reporter activity.

1,3-Diaminopropane, a three carbon diamine, is an ornithine decarboxylase inhibitor.

1,2-Dipalmitoyl-sn-glycerol 3-phosphate is a phosphatidic acid.

1,2,3,4,5,6-Hexabromocyclohexane is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range.

1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases.

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