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Cat. No. Product Name Field of Application Chemical Structure
DC34467 FAD-Na2
FAD-Na2 is a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases.
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DC36785 Syrosingopine
Syrosingopine has been found to potentiate the anticancer activity of widely used diabetic drug metformin by sensitizing cancer cells to metformin.
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DC36972 3'-Adenylic acid
3'-Adenylic acid is a bioactive chemical.
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DC38029 Dienestrol diacetate
Dienestrol diacetate is a derivative of the synthetic non-steroid phenolic compound, DIENESTROL, which exhibits estrogenic activities.
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DC31824 Prochlorperazine Dimaleate
Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo. It is also a highly potent typical antipsychotic, 10–20 times more potent than chlorpromazine. Prochlorperazine dimaleate is also used to treat migraine headaches.
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DC36278 Gliovirin
Gliovirin is a fungal metabolite with fungicidal, antimicrobial and anti-inflammatory activities. It is active against the plant pathogenic fungus P. ultimum and the parasite T. brucei brucei, but has no effect on the plant pathogenic fungi R. solani, P. omnivorum, T. basicola, R. arrhizus, and V. dahliae or the bacteria B. thuringiensis, P. fluorescens, and X. malvacearu. Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 and protein levels of IL-2 in Jurkat cells.
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DC36402 SPQ
SPQ is a fluorescent chloride indicator. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin, and PMA in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2.
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DC36206 (-)-AMPA
(R)-AMPA is an inactive isomer of (RS)-AMPA (MedKoo Cat# 573831).
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DC36205 L-(S)-AMPA
(S)-AMPA is an active isomer of (RS)-AMPA and selective AMPA agonist.
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DC36494 D21-2393
D21-2393 is known as Edoxaban 4-Carboxylic Acid. Subjects received a single-oral-dose of edoxaban 30-90?mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active metabolite D21-2393. Meanwhile, PT, INR, aPTT were measured pre- and post-dose. Safety was assessed. 4.?The effects of edoxaban on all pharmacodynamic biomarkers were concentration-dependent and linearly-correlated to plasma level of the compound. Minor bleeding was the most commonly reported adverse events.
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DC36834 Sitostanol
Sitostanol is a saturated sterol found in a variety of plants, including corn, wheat, and rice and reduces cholesterol uptake in rats and rabbits.
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DC34331 SG-209
SG-209 is a potassium channel opener.
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DC34148 Delapril
Delapril is an angiotensin-converting enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to angiotensin II.
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DC37109 2-Chloro-6-nitrotoluene
2-Chloro-6-nitrotoluene is a biochemical.
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DC34653 Ametryn
Ametryn is a methylthiotriazine based herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is used to control broadleaf weeds and annual grasses in pineapple, sugarcane and bananas.
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DC37276 Hydroxytoluic acid
Hydroxytoluic acid is a biochemical.
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DC36379 Antibiotic 1166C
Hygrolidin is a macrocyclic lactone that inhibits proliferation of DLD-1 colon cancer, LNCaP prostate cancer, and K562 leukemia cells. Hygrolidin induces the expression and levels of p21 in DLD-1 cells, but not WI-38 fibroblasts, and leads to cell accumulation in the G1 and S phases without inducing apoptosis. It has antiparasitic activity against T. cruzi, L. donovani, and T. b. brucei but also induces cytotoxicity in HepG2 cells.
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DC37083 Acenaphthene
Acenaphthene is a polycyclic aromatic hydrocarbon consisting of naphthalene with an ethylene bridge connecting positions 1 and 8.
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DC36476 6-Aminophenanthridine
6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz. 6-Aminophenanthridine inhibits protein folding activity of the ribosome (PFAR) by directly competing with protein substrates for the active site and decreases the yield of refolded protein without affecting the refolding rate. It prevents progressive wing position defects in a Drosophila model of oculopharyngeal muscular dystrophy (OPMD) when larvae are raised on medium containing doses ranging from 300 to 400 μM and in adults following dietary administration of 1-3 mM doses. 6-Aminophenanthridine also reduces muscle degeneration and decreases the number of nuclear inclusions in thoracic muscle in a Drosophila model of OPMD.
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DC37195 NSC 31211
Pindone is an anticoagulant drug for agricultural use.
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DC36851 Diflufenican
Diflufenican induces inhibition of phytoene desaturase gene expression in carrot cell cultures that results in an increased production of phytoene.
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DC34389 MAL2-11B
MAL2-11B is an inhibitor of Simian Virus 40 replication. It acts by targeting the molecular chaperone function and ATPase activity of T antigen. MAL2-11B is also a MAL3-101 precursor.
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DC36555 Bis(p-chlorophenyl)acetic acid
Bis(p-chlorophenyl)acetic acid is a biochemical.
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DC38056 Bensulfuron-methyl
Bensulfuron-methyl is a herbicide.
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DC34114 Ingenol 3-Hexanoate
Ingenol 3-Hexanoate novel potent reactivator of latent HIV-1.
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DC37053 Buclizine
Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.
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DC35621 Alkynyl Myristic Acid
Alkynyl Myristic Acid is a non-PEG crosslinker which can be used to identify and characterize post-translational myristylated proteins with Click Chemistry.
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DC34557 CI928
Quinaprilat is an angiotensin converting enzyme inhibitor.
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DC34117 GSK983
GSK983 is a potent broad-spectrum antiviral. It blocks cell proliferation and dengue virus replication by inhibiting the pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase (DHODH).
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DC37075 Quintozene
Quintozene, it was introduced to the agricultural world in the 1930s in Germany by Bayer AG as a substitute to mercurial pesticides.
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