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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC40234 | JH295 |
JH295 is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 inhibits cellular Nek2 via alkylation of Cys22. JH295 is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint.
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| DC40223 | 2-Undecanol |
2-Undecanol (Undecan-2-ol) is a male specific volatile identified from the sap beetle Lobiopa insularis. 2-undecanol is a flower emitted volatile, used by various species of Hymenoptera as a pheromone component.
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| DC40218 | N-Heptanoyl-L-homoserine lactone |
N-Heptanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acyl-homoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria.
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| DC40215 | Vanillic acid glucoside |
Vanillic acid glucoside is isolated from the fruits of C. annuum as well as the leaves of various additional plants. Vanillic acid glucoside belongs to a class of compounds known as hydrolyzable tannins and can be phytotoxic against different species.
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| DC40212 | Ganglioside GM3 sodium salt |
Ganglioside GM3 sodium salt is a sialylated membrane-based glycosphingolipid that regulates insulin receptor signaling via direct association with the receptor. Ganglioside GM3 sodium salt possesses powerful effects on cancer development and progression.
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| DC40204 | Pronase E (Activity≥4000 U/mg) |
Pronase E (Activity≥4000 U/mg) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids.
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| DC40203 | Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside |
Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is an enantiomer of Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside. Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is a derivative of L-ribose.
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| DC40202 | Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside |
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside, obtained from D-ribose, is an intermediate for the synthesis of riboside-containing arsenic compound.
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| DC40196 | Leukotriene E4 |
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
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| DC40193 | Leukotriene C4 D5 |
Leukotriene C4 D5 is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4.
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| DC40189 | N1,N12-Diacetylspermine dihydrochloride |
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection.
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| DC40185 | Thromboxane B2 |
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation.
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| DC40173 | Serelaxin |
Serelaxin (RLX-030), a recombinant form of human gene-2 relaxin targeting the RLN receptor, is a vasoactive peptide hormone with an antifibrotic activity.
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| DC40158 | VIT-2763 |
VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia.
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| DC40149 | Macropa-NH2 TFA |
Macropa-NH2 TFA is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases.
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| DC40120 | (R)-Gyramide A hydrochloride |
(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 μM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV.
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| DC40114 | Modipafant |
Modipafant (UK-80067), the (+)-enantiomer of UK-74505, is a potent, orally active, and selective platelet-activating factor (PAF) antagonist. Modipafant exhibits approximately double the intrinsic potency of UK-74505.
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| DC40113 | (Rac)-Modipafant |
(Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. (Rac)-Modipafant prevents dengue infection.
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| DC40111 | Protease K |
Protease K is a nonspecific serine protease that is useful for general digestion of proteins. Protease K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures.
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| DC40110 | β-Tocotrienol |
β-Tocotrienol is one form of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol.
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| DC40094 | Iron dextran |
Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals.
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| DC40089 | MIF-1 TFA |
MIF-1 TFA, an antibiotic with melanin synthesis inhibitory activity, strongly inhibits melanin formation in Streptomyces bikiniensis NRRLB-1049 and B16 melanoma cells.
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| DC40088 | S-(+)-Arundic Acid |
S-(+)-Arundic Acid ((S)ONO-2506) is the S-enantiomer of Arundic Acid. Arundic acid is an astrocyte-modulating agent, has the potential for stroke and Alzheimer’s disease research.
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| DC40082 | Yubeinine |
Yubeinine is an alkaloid, isolated from the bulbs of Fritillaria yuminensis.
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| DC40071 | Nepinalone hydrochloride |
Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity.
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| DC40049 | (Rac)-Azide-phenylalanine |
(Rac)-Azide-phenylalanine is a racemate of Azide-phenylalanine. Azide-phenylalanine is a phenylalanine derivative and a non-natural amino acid. Azide-phenylalanine can be site-specifically incorporated into proteins and used to label proteins.
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| DC40048 | Tetraphenylporphyrin |
Tetraphenylporphyrin (TPP;Tetraphenylporphine;meso-Tetraphenylporphyrin) is a symmetrically substituted porphyrin-based?heterocyclic compound and used as a structural block for supramolecular?synthesis. Tetraphenylporphyrin derivatives can be used for cancer research.
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| DC40047 | (2S)-Octyl-α-hydroxyglutarate |
(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.
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| DC40036 | NAI-N3 |
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment).
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| DC40029 | Ceefourin 1 |
Ceefourin 1 is a potent and highly selective multidrug resistance protein 4 (MRP4) inhibitor. Ceefourin 1 inhibits transport of a broad range of MRP4 substrates, yet are highly selective for MRP4 over other ABC transporters. Ceefourin 1 is a benzothiazol and primarily as chemosensitizers for high-risk neuroblastoma.
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