Picromycin is a 14-membered macrolide antibiotic and inhibitor of Prolyl endopeptidase (PREP). Pikromycin shows activity against gram-positive bacteria including mycobacteria.

Amino-PEG10-acidis a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Propargyl-PEG1-SS-PEG1-propargyl is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG Linker.

Azido-PEG3-phosphonic acid is a PEG derivative containing an azide group and a phosphonic acid. The azide group enables Click Chemistry andthe phosphonic acid can be a potential ligand choice. The hydrophilic PEG spacer increases solubility in aqueous media.

NH-bis(PEG2-t-butyl ester) is a PEG derivative containing an amino group with two t-butyl esters. The amino groups is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates.

Aspergillimide is a fungal metabolite that reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.

A 127722 is highly potent and a selective ETA endothelin receptor antagonist (IC50 values are 0.11 nM and 98 nM for human ETA and ETB receptors, respectively)that attenuates hypoxia-induced pulmonary hypertension in rats.

NBD-Pen high-sensitivity, specific fluorescence probe for lipid radicals. NBD-Pen directly detected lipid radicals in living cells by turn-on fluorescence. In a rat model of hepatic carcinoma induced by diethylnitrosamine (DEN), NBD-Pen detected lipid radical generation within 1 hour of DEN administration.

Chloramben-sodium is an herbicide.

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7?. The alkyne can be conjugated to a variety of azides via copper-catalyzed Click chemistry. The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

3-Hydroxydecanoic acid, (3R)- is active against Bacillus subtilis, Escherichia coli and Staphyllococcus aureus. fungistatic activity against Candida albicans.

PDD 00017238 is a PARG inhibitor.

DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities.

t-Boc-aminooxy-PEG3-propargyl is a crosslinker containing a propargyl group and t-Boc-aminooxy group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.

Bromo-PEG4-azide is a PEG derivative containing a bromide group and a terminal azide. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Propargyl-PEG6-acid is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

L-3373 is a bioactive chemical.

R 121919 hydrochloride is a high affinity CRF1 antagonist and is orally bioavailable.

Tos-PEG6-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Oxolamine citrate is a antiinflammatory drug used as a cough suppressant.

ACPT-1 is an agonist of group III mGlu receptors.

Tetragastrin is the C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin.

PDD-00017272 is a potent poly (ADP ribose) glycohydrolase (PARG) inhibitor.

DBC is a ubiquitous environmental pollutant, inducing significant DNA strand break levels and micronuclei in HepG2 cells.

Thiol-PEG6-alcohol is a PEG derivative containing a thiol group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Fenoterol is β2-Adrenergic receptor (β2-AR) agonist. Fenoterol is chemically closely related to metaproterenol (orciprenaline). It has a higher bronchodilating potency than metaproterenol, albuterol (salbutamol in Europe) or terbutaline. The beta 2 selectivity of fenoterol at normal oral and inhaled doses is the same as for albuterol and terbutaline. Its pharmacodynamic effects are similar to those of other selective beta 2-adrenoceptor agonists.

Curcumenol is a sesquiterpene isolated from Curcuma zedoaria is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities.

Pentalysine is a peptide.

AZ 5704 is a potent and selective ATM kinase inhibitor.