Aminooxy-PEG3-bromide HCl salt is a PEG derivative containing an aminooxy group and a bromide group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.

t-Boc-aminooxy-PEG1-propargyl is a PEG derivative containing a propargyl group and t-Boc-aminooxy group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers can be useful in the development of antibody drug conjugates.

Fmoc-aminooxy-PEG4-acid is an Aminooxy PEG Linker. Aminooxy-PEGs may be useful in bioconjugation experiments.

Aminooxy-PEG1-propargyl HCl salt is a PEG derivative containing a propargyl group and an aminooxy group. The aminooxy group reacts with an aldehyde or ketone group to form a stable oxime linkage. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG derivatives may be useful in the development of antibody drug conjugates as well as drug delivery.

t-Boc-N-amido-PEG3-thiol is a PEG derivative containing a Boc-protected amino group and a thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.

Acid-PEG9-NHS ester is a PEG derivative containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

TAMRA-PEG4-DBCO is a PEG derivative containing a TARMA dye and a DBCO group, which enables Click Chemistry. The TAMRA dye has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. DBCO will react with azide functionalized compounds or biomolecules without catalyst to form a stable triazole linkage, which is an ideal alternative to copper intolerant applications. The hydrophilic PEG spacer increases solubility in aqueous media.

Biotin-PEG5-NH-Boc is a Biotin PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

t-boc-N-amido-PEG5-amine is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. PEG Linkers may be useful in the development of antibody drug conjugates.

Magnesium lactate is a buffering agent and magnesium donor

Desmethylselegiline is an Enzyme Inhibitor.

ZINC05626394 is a Cytochrome b5 reductase 3 (CYB5R3) inhibitor. It acts by increasing NO bioavailability.

Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks 68% of translation. Cbz-B3A binds to ubiquilins 1, 2, and 4.

Diazo Biotin-PEG3-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4).

JTP 103237 is a potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor.

FHZ is a highly selective, cell-permeable, non-cytotoxic probe for dual channel detection of (OH radical) and HOCl in live cells and zebrafish embryos.

AA-5HT, also known as Arachidonoyl serotonin or N-arachidonoyl-serotonin, is an inhibitor of fatty acid amide hydrolase (FAAH). It has analgesic properties and acts as an antagonist of the TRPV1 receptor. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion.

(p-Acetylphenoxy)acetic acid is a biochemical.

β-Apooxytetracycline is a potential impurity of oxytetracycline. β-Apooxytetracycline is a degradation product formed from oxytetracycline via acid hydrolysis. β-Apooxytetracycline is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.

Bemotrizinol is a UVA absorber used as a topical sunscreen.

XY 018 is a RORγ antagonist that suppresses androgen receptor expression in prostate cancer cell lines and inhibits growth of tumors in androgen receptor-positive xenograft models.

Dacisteine, also known as D-cysteine. protects primary cultures of cerebellar neurons from oxidative stress induced by hydrogen peroxide and attenuates ischaemia-reperfusion injury in the kidney more than L-cysteine. A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells. provides a new therapeutic approach to deliver hydrogen sulphide to specific tissues.

Propargyl-PEG4-(CH2)3-acid is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

m-PEG4-phosphonic acid ethyl ester is a PEG Linker.

Propargyl-PEG4-(CH2)3-methyl ester is a PEG derivative containing a propargyl group and a methyl ester. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery.

Mc-Val-Ala-PAB is a useful linker to make antibody-drug-conjugate (ADC) for targeting drug delivery.

PC Biotin-PEG3-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. Captured biomolecules can be efficiently photoreleased using near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Actarit is a drug that has been shown to suppress disease activity of rheumatoid arthritis (RA). Actarit reduces spontaneous tumor necrosis factor-alpha and interleukin 1beta secretion by primary synovial cells of patients with RA. Actarit likely acts on RA synovial cells to reduce cell-cell interactions with autologous synovium infiltrating lymphocytes and to inhibit proinflammatory cytokine and MMP production, leading to amelioration of symptoms of RA.

Ambroxol is a metabolite of Bromhexine that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

(+)-Pinanediol is an effective inducer of melanogenesis. It acts by inducing higher levels of pigmentation and synthesis of nitric oxide (NO) in S91 cells.