Selective S1P3 agonist

CDK9 inhibitor, inhibiting transcription of GAPDH

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Novel antibiotic sensitizer, promoting the rearrangement of the bacterial membrane that enables hydrophobic antibiotics to permeate, strongly sensitizing Gram-negative bacteria to linezolid (Lzd), rifampicin (Rif), or clarithromycin (Clr)

First-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), promoting the differentiation of OPCs into mature oligodendrocytes in vitro

First-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), promoting the differentiation of OPCs into mature oligodendrocytes in vitro

Novel inhibitor of 70S ribosome by obstructing the peptide exit tunnel

Self-assembling peptide, forming a hydrogel matrix to support growth of cells in the presence of an ionic solution, enhancing chondrogenic differentiation of bone marrow stromal cells (BMSCs)

Novel NF-κB inhibitor and lipopolysaccharide (LPS)-induced nitric oxide production inhibitor

Potent D3 receptor antagonist with high 5-HT1A receptor affinity

Novel specific inhibitor of MYC

Novel TRPV1 antagonist

Novel ROS1 kinase inhibitor

Novel ROS1 kinase inhibitor

Novel potent and selective inhibitor of kir1.1 channels

Novel inducer of the ISG54 promoter, causing IRF-3 translocation

Novel Max-binding modulator, attenuating Myc-driven transcription and stabilizing the Max homodimer

Novel KIF18A inhibitor, causing significant mitotic arrest in vivo, binding at the interface of KIF18A and tubulin

Novel FGFR2 inhibitor, enhancing the chemosensitivity of drug-resistant gastric cancer cell lines

Novel anti-inflammatory and antioxidant agent, significantly decreasing blood glucose, triglycerides, and cholesterol and increased insulin

Inhibitor of Aβ-induced inflammation

Novel Pim-1 kinase Inhibitor, dose-dependent decreasing the viability of LS174T and HCT-116 cells

Novel potent peptide dual agonist of opioid/neurokinin 1 receptor

Novel and potent factor Xa inhibitor

Potent and selective adenosine A1 antagonist with renal protective and diuretic activities

Phosphate acceptor peptide substrate for cAMP-dependent protein kinase

Potent and selective KDM5 inhibitor

Potent and selective KDM5 inhibitor

Novel KDM4 inhibitor

Novel selective KDM4C inhibitor