Novel partial agonist of the benzodiazepine receptor

Blocker of the activity of human neutrophil elastase (NE), human proteinase-3, human macrophage metalloelastase, mouse macrophage metalloelastase and Pseudomonas aeruginosa elastase

Potent leukotriene inhibitor

Novel potent inhibitor of human pancreatic cancer cells

Novel inhibitor of the TWEAK-Fn14 signaling cascade

Novel inhibitor of α-synuclein amyloid aggregation for the treatment of Parkinson's disease

Novel γ-secretase modulator photoaffinity probe, identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species

Novel Migration Inhibitory Factor (MIF) inhibitor, binding at the allosteric and tautomerase sites, blocking MIF's tautomerase CD74 receptor binding, and pro-inflammatory activities

Novel cell-permeable attenuated cationic amphiphilic lytic (ACAL) peptide, efficiently bring immunoglobulin G (IgG) and other functional proteins into cells

Nonpeptide agonist of angiotensin AT1 receptor

Potent inhibitor of LpxC and lipid A biosynthesis

Selective T-type Ca(2+) channel blocker with anti-proliferative effects against various cancer cells

Novel inhibitor of the Wnt/ß-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppres

Ras destabilizer, targeting the Wnt/ß-catenin pathway and inhibiting development of metastatic colorectal cancer

Novel Preferable Phosphodiesterase 4B (PDE4B) Inhibitor, Decreasing Cocaine-Mediated Reward Properties in Vivo

Novel neuroprotectant, inhibiting Kv2.1-syntaxin molecular interaction

Potent Kv1.5 inhibitor

Novel protein farnesyltransferase inhibitor

Novel potent and selective inhibitor of Hsp90β

Novel selective DYRK1A inhibitor

Hypoxic cell radiosensitizer

Thyroid hormone receptor β (TRβ) selective agonist

TXA2/prostaglandin endoperoxide receptor antagonist

Potent and selective inhibitor of ABHD6

Novel modulator of kinesin spindle protein (KSP)/Eg5, activating KSP-catalyzed ATP hydrolysis in the absence of microtubules yet inhibiting microtubule-stimulated ATP hydrolysis by KSP

Novel, highly potent, and metabolically stable peptide inhibitor of syntenin, Inhibiting Glioblastoma

Novel inhibitor of transcriptional activity in Chlamydia trachomatis

Ligand of the sigma receptor

Ligand of the sigma receptor

Selective ligand of the sigma-1 receptor