Novel activator of the bone marker alkaline phosphatase (ALP), markedly promoting osteoblast differentiation, including expression of Runx2, Osterix, and Osteocalcin, mediating osteogenesis through activation of p38-β

Potent antagonist of GABA A receptors that contain alpha1 and beta2 subunits

Natural full D1 dopamine receptor agonist

Long-lasting prodrug of nalbuphine, acting as a moderate-efficacy partial agonist or antagonist of the μ-opioid receptor and as a high-efficacy partial agonist of the κ-opioid receptor

Inhibitor of Topoisomerase>DNA topoisomerase II; very potent cytotoxic antitumor agent

Anti-infective agent against certain protozoa such as Babesia, Trypanosoma, Cytauxzoon, and certain bacteria including Brucella and Streptococcus

Novel analog of etomidate, potently inhibiting 11-beta-hydroxylase without GABAA receptor positive modulatory and sedative-hypnotic activities

Serotonin antagonist and histamine antagonist

Novel inhibitor of AMA1-RON2 interaction, blocking merozoite invasion from schizont-infected RBCs; Antidepressant; Acetylcholinesterase inhibitor

Building Block

Building Block

Vasodilator for the treatment of cardiopathy and renal disorders, acting as an adenosine reuptake inhibitor.

Novel lipid-based, high-density, environmentally sensitive (HIDE) probe

Novel lipid-based, high-density, environmentally sensitive (HIDE) probe

Unique antimigration and antiangiogenic agent

Closely related co-metabolite of cyclosporin A

Competitive nicotinic receptor antagonist

D1-like full agonist with similar affinity for D1 and D5, and roughly 10-fold selectivity over D2-like receptors

Novel dose-dependent inhibitor of the SARS-CoV-2 Mac1 Macrodomain

Corticosteroid Hormone Receptor Agonist

Agonist of the androgen receptor (AR); #333333; font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans:

Antiemetic agent used in the treatment of vomiting and vertigo

Muscle relaxant, causing general central nervous system depression, relieving pain caused by strains, sprains, and other musculoskeletal conditions

Novel inhibitor of CP4H activity in cultured cells at concentrations that do not cause iron deficiency

Novel inhibitor of CP4H activity in cultured cells at concentrations that do not cause iron deficiency

Inhibitor of DTDST inhibitor, a novel intestinal epigallocatechin gallate (EGCg) transporter

Natural Tat inhibitor, blocking HIV-1 transcription by specifically targeting the viral transactivator, Tat

Selective herbicide for the control of dicot weeds

Non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions

Major biliary metabolite of Diclofenac, a nonsteroidal antiinflammatory drug and COX inhibitor