Novel highly potent and selective acetyl-CoA carboxylase 1 (ACC1) inhibitor (hACC1: IC 50 =0.58nM, hACC2: IC 50 >10000nM)

Novel Selective, irreversible, and Rapid Cell-Permeable Inhibitor of Human Caspase-3

Novel, cell-permeable, potent O-GlcNAc transferase (OGT) inhibitor

Novel metabolic oligosaccharide engineering (MOE) reagent, being an efficient chemical tool to probe protein glycosylation

Novel metabolic oligosaccharide engineering (MOE) reagent, being an efficient chemical tool to probe protein glycosylation

Novel potent and specific inhibitor of janus kinase 2 (JAK2)

Novel potent and selective multidrug resistance-associated protein 1 (MRP1, ABCC1) modulator

Novel benzodiazepine receptor partial inverse agonist

Novel potent, nontoxic, and highly selective breast cancer resistance protein (BCRP) inhibitor

Prodrug of 4FGalNAz to label a variety of proteins in mammalian cells without perturbing endogenous glycosylation pathways and primarily act as a substrate for O-GlcNAc transferase (OGT)

Novel potent, nontoxic, and highly selective breast cancer resistance protein (BCRP) inhibitor

Novel inhibitor of Mycobacterium tuberculosis (Mtb), selectively killing Mtb at acidic pH and potentiating the bactericidal activity of isoniazid, clofazimine, and diamide

Novel inhibitor of Mycobacterium tuberculosis (Mtb) growth at acidic pH, killing Mtb by selectively depleting free thiols at acidic pH

Orally bioavailable M(1) muscarinic receptor allosteric agonist improving cognitive performance in an animal model

Novel potent, nontoxic, and highly selective breast cancer resistance protein (BCRP/ABCG2) inhibitor

Selective NPFF(1) receptor ligand

Novel blocker of HOX antisense intergenic RNA (HOTAIR) by abrogating the scaffold interaction with EZH2

Novel potent, nontoxic, and highly selective breast cancer resistance protein (BCRP) inhibitor

Novel potent and selective KOR antagonist, potentially stabilizing the bioactive conformation and enhancing its metabolic stability

Novel agonist of STING (stimulator of interferon genes) with enhanced binding to STING and cellular function

Inhibitor of protein synthesis with potent activity against multidrug-resistant Gram-positive bacterial strains

Selective dopamine D3 receptor antagonist

Orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction

Potent nicotinic acetylcholine receptor agonist

Hghly selective antagonist for endothelin ET A receptor

Novel PARP inhibitor

Agonist of neural nicotinic acetylcholine receptors

Potent and selective histamine H3 receptor antagonist

Natural hACE2 inhibitor with strong affinity for the exopeptidase site of hACE2

Natural TMPRSS2 inhibitor