ZINC 39395747|ZINC39395747;ZINC-39395747

Cas No.:	1801163-44-9
Chemical Name:	ZINC 39395747
SMILES:	C1C=C2C(=CC=1)N[C@@H](SCC1=CC(NC(=S)N1)=O)O2
Formula:	C₁₂H₁₁N₃O₂S₂
M.Wt:	293.364639520645
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM; significantly increases NO bioavailability in renal vascular cells, augments renal blood flow, and decreases systemic blood pressure in response to vasoconstrictors in spontaneously hypertensive rats.

Cat. No.	Product name	Field of application
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