Cas No.: | 68729-05-5 |
Chemical Name: | 4-(4-Benzylphenyl)-1,3-thiazol-2-amine |
Synonyms: | Arm1;4-(4-benzylphenyl)-1,3-thiazol-2-amine;1V6;4l2l;ARM-1;Oprea1_716646;Oprea1_110562;BBL020883;STK893589;BDBM50197084;4-(4-benzylphenyl) thiazol-2 amine;2-Thiazolamine, 4-[4-(phenylmethyl)phenyl]-;Q27452475 |
SMILES: | S1C(N([H])[H])=NC(=C1[H])C1C([H])=C([H])C(=C([H])C=1[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H] |
Formula: | C16H14N2S |
M.Wt: | 266.3608 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM; selectively blocks conversion of LTA4 into LTB4, sparing the enzyme's anti-inflammatory aminopeptidase activity; represents a new class of LTA4 hydrolase inhibitor that holds promise for improved anti-inflammatory properties. |