PF-06305591|PF06305591;PF 06305591

Cas No.:	1449473-97-5
Chemical Name:	(2R,3S)-3-amino-3-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)-2-methylpropanamide
Synonyms:	PF06305591;PF 06305591
SMILES:	C(N)(=O)[C@@H](C)[C@@H](N)C1=NC2=CC(C(C)(C)C)=CC=C2N1
Formula:	C₁₅H₂₂N₄O
M.Wt:	274.368
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PF-06305591 (PF06305591) is a potent, highly selective selective NaV1.8 blocker with IC50 of 15 nM, displays no significant activity against other sodium channel subtypes, K+ channels and Ca2+ channels; displays excellent preclinical in vitro ADME and safety profile.

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