(S,R,S)-AHPC-C6-NH2 hydrochloride|CAS 2360522-76-3|DC Chemicals

Cas No.:	2360522-76-3
Chemical Name:	(S,R,S)-AHPC-C6-NH2 hydrochloride
SMILES:	[H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCN)=O
Formula:	C₂₉H₄₄ClN₅O₄S
M.Wt:	594.21
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Description:	(S,R,S)-AHPC-C5-NH2 hydrochloride (VH032-C5-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C5-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
Target:	VHL
In Vitro:	(S,R,S)-AHPC-C5-NH2 hydrochloride (VH032-C5-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader, XF038-161A, example 6, extracted from patent WO2019173516A1[1].
References:	[1]. Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

Cat. No.	Product name	Field of application
DC39625	(S,R,S)-AHPC-PEG4-NH2 hydrochloride	VH 032 Linker 2 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1.
DC50079	Thalidomide-O-amido-C5-NH2	Thalidomide-O-amido-C5-NH2 is a novel PROTAC building block.
DC50078	(S,R,S)-AHPC-Me-C8-NH2	(S,R,S)-AHPC-Me-C8-NH2 is a novel PROTAC building block.
DC50077	(S,R,S)-AHPC-Me-C4-NH2	(S,R,S)-AHPC-Me-C4-NH2 is a novel PROTACA building block.
DC50076	(S,R,S)-AHPC-Me-C3-NH2	(S,R,S)-AHPC-Me-C3-NH2 is a novel PROTAC building block.
DC50075	(S,R,S)-AHPC-Me-C2-NH2	(S,R,S)-AHPC-Me-C2-NH2 is a novel PROTAC building block.
DC50074	(S,R,S)-AHPC-Me-C1-NH2	(S,R,S)-AHPC-Me-C1-NH2 is a novel PROTAC Building block.
DC50070	(S,R,S)-AHPC-PEG2-NH2 (E3 ligase Ligand-Linker Conjugates 6 Free Base)	(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
DC50069	(S,R,S)-AHPC-PEG4-NH2(E3 ligase Ligand-Linker Conjugates 7)	(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
DC50068	(S,R,S)-AHPC-Me-C10-NH2	(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432