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Cell Cycle/DNA Damage

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Cat. No. Product Name Field of Application Chemical Structure
DC11863 CA224
A non-planar analogue of fascaplysin that selectively inhibits CDK4/cyclin D1 with IC50 of 5.5 uM.
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DC11851 Clitocine
A naturally occurring nucleoside analog that possesses antitumor activity, also is a potent and efficacious readthrough agent.
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DC11718 Debromohymenialdisine
A marine sponge alkaloid that inhibits Chk1 and Chk2 with IC50 of 3 and 3.5 uM, respectively.
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DC11779 TNKS-IN-41
A highly potent and selective tankyrase inhibitor with pIC50 of 8.5 and 8.1 for TNKS1 and TNKS2, respectively.
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DC11932 GPX-150
A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM.
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DC11874 CDK12 inhibitor E9 racemate
A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux.
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DC11873 CDK12 inhibitor E9 R-isomer
A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux.
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DC8944 5-Fluorouracil
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
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DCK-004 corilagin
>98%,Standard References
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DCZ-158 CALCIUML-5-METHYLTETRAHYDROFOLATE
>98%,Standard References
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