HCQ-3 NHS has a maximum absorbance at 672 nm and can be placed at either the 5' or 3' end of an oligonucleotide or within its interior. Oligonucleotides labeled with BHQ-3 are employed in numerous applications, such as dual-labeled fluorescent probes for real-time PCR. This dark quencher has a strong absorption range from 620 to 730 nm, enabling it to quench fluorophores that emit fluorescence within this range, like Quasar 670 and Quasar 705 dyes.

HCQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

HCQ-1 NHS directly labeled by fluorescently labeled nucleotide.

Quasar 705 fluorophore is an indocarbocyanine dye. It emits fluorescence in the deep - red region of the visible spectrum. This fluorescence can be effectively quenched by BHQ - 2 or BHQ - 3 dyes. The excitation wavelength of Quasar 705 is 690 nm, and its emission wavelength is 705 nm.

Quassar 670 NHS emits red fluorescence. It has an excitation wavelength of 670 nm and an emission wavelength of 644 nm.

Sulfo-Cyanine5.5 NHS ester is an amine-reactive active ester of a sulfonated far-infrared Cyanine5.5 fluorophore (an analogue of Cy5.5). This reagent is the preferred choice for labeling antibodies, sensitive proteins, and other substances in reactions that require a pure water environment or minimal addition of organic co-solvents. The dye is highly suitable for non-invasive in vivo near-infrared imaging and applications that demand a low fluorescence background.

Cyanine 5.5 NHS is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds.

Sulfo-Cyanine 7 NHS is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.

Sulfo - Cyanine 3 NHS, a water - soluble and amine - reactive compound, can efficiently label proteins and polypeptides in pure aqueous solutions without the need for organic co - solvents. This makes it an ideal option for proteins with low solubility and those prone to denaturation. Moreover, the Sulfo - Cyanine 3 NHS ester can serve as a substitute for Cy3, Alexa Fluor 546, and DyLight 549, offering a practical alternative in various experimental and research settings.

6-JOE NHS is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides

6 - NED can be employed in multiple applications, including fragment analysis, gene expression studies, genotyping, and PCR techniques. 6 - NED NHS is a highly stable fluorescent probe. It has seen widespread use in the field of labeling amino - modified oligonucleotides, contributing to more accurate and efficient research efforts in relevant biological and genetic studies.

6-HEX NHS is the amine-reactive succinimidyl ester of 6-HEX acid. It has found extensive applications in nucleic acid sequencing and related research fields. This NHS ester belongs to a class of amine-reactive dyes. It is utilized for labeling amine groups in various target molecules, such as proteins, peptides, and amino-modified oligomers.

Fluorescein isothiocyanate(FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry.

WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor. WEE1-IN-10 shows inhibitory activity on LOVO cell growth, with an IC50 of 0.524 μM. WEE1-IN-10 can be used for the research of diseases caused by abnormal activity of Wee1.

DL-5-Indolylmethylhydantoin can be used as a substrate for the enzymatic production of L-tryptophan in some specific bacteria.

Wnt pathway activator 2 (compound 2) is a potent Wnt activator with an EC50 of 13 nM.

JZL184 is a strong and selective inhibitor of Monoglyceride Lipase

YO-01027 (Dibenzazepine, DBZ) is a dipeptidic g-secretase inhibitor with IC50 of 2.6 and 2.9 nM for APPL and Notch, respectively.

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.

CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.

E-64c is a synthetic analog of E-64, a potent and irreversible cysteine protease inhibitor isolated from Aspergillus japonicus.

UNC-0224 is a potent inhibitor of G9a histone lysine methyltransferase (IC50 = 15 nM).

KML29 is an O-hexafluoroisopropyl carbamate analog of JZL 184 that potently and selectively inhibits MAGL (IC50s = 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively) over FAAH (IC50s >50 μM).