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Cat. No. Product Name Field of Application Chemical Structure
DC10536 KML-29 Featured
KML29 is an O-hexafluoroisopropyl carbamate analog of JZL 184 that potently and selectively inhibits MAGL (IC50s = 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively) over FAAH (IC50s >50 μM).
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DC10726 Fuscoside Featured
OPC-21268 is a vasopressin 1 receptor antagonist potentially for the treatment of heart failure and hypertension.
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DC8806 NS-398 Featured
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2).
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DC23559 Bay K-8644 Featured
Bay K-8644 is a potent L-type calcium channels (LTCCs) activator with EC50 of 17.3 nM, has positive inotropic, vasoconstrictive and behavioral effects in vivo.
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DC10375 YU238259 Featured
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.
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DC7658 C646 Featured
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases.
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DC8383 Dp44mT Featured
Dp44mT is a potent iron chelator, which shows selective antitumor activity.
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DC9818 Azoramide Featured
Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity.
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DC7103 LY2603618(IC-83) Featured
LY2603618(IC-83) is a potent and selective small molecule inhibitor of Chk1 protein kinase activity in vitro (IC50=7 nM) and the first selective Chk1 inhibitor to enter clinical cancer trials.
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DC21511 Pico145 Featured
Pico145 is a highly potent, subtype-selective TRPC1/4/5 channels inhibitor with potency ranged from 9 to 1300 pM, depending on the TRPC1/4/5 subtype and activation mechanism.
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DC10539 POL1 inhibitor(POL1-IN-1) Featured
POL1-IN-1 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription.
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DC7357 Anamorelin Featured
Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.
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DC73220 Allopole-A Featured
Allopole-A is the first allosteric, specfic inhibitor of the noncatalytic polo-box domain (PBD) of PLK1 (Polo-like kinase 1) with IC50 of 2.5 nM in FP-based assays, Allopole-A is the active form of Allopole.
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DC46528 MCT4-IN-1 Featured
MCT4-IN-1 is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MCT4-IN-1 targets to the cytosolic domain of MCT4. MCT4-IN-1 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MCT4-IN-1 has the potential for MCT4 transporter inhibition research.
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DC9258 PD168393 Featured
PD168393 is potent, cell-permeable, irreversible and selective inhibitor of EGF receptor (EGFR) tyrosine kinase and ErbB2.
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DC23863 eCF506 Featured
A highly potent, selective, orally available Src family kinase inhibitor with IC50 of <0.5 nM, <0.5 nM and for Src, Yes and Fyn kinases respectively, >950-fold selectivity for Src over ABL.
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DC70430 GDC-0334 Featured
GDC-0334 (GDC0334) is a highly potent, selective, orally bioavailable TRPA1 antagonist with IC50 of 1.7 nM in cell-based assays.GDC-0334 demonstrated potent TRPA1 inhibition in several species, including human (IC50=1.7 nM), cynomolgus (IC50=3.6 nM), mouse (IC50=2.7 nM), guinea pig (IC50=11.1 nM), and dog (IC50=102 nM).GDC-0334 displays good selectivity against human TRPV1, TRPM8, and TRPC6 (all IC50s>10 uM).GDC-0334 also inhibits calcium flux in human primary cells, HASMCs and HLFs, treated with the TRPA1 agonist AITC.GDC-0334 suppresses AITC-induced edema in vivo in rat (1-10 mg/kg), reduces OVA-induced asthma model in rats and guinea pigs and guinea pig model of cough.GDC-0334 is a potent inhibitor of AITC-induced dermal blood flow (DBF) in vivo in rats and guinea pigs, reduces AITC-induced perfusion and nocifensive behavior in rats and itch and pain scores in humans.
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DC67929 1-bromotriacontane Featured
DC28399 Traumatic acid Featured
Traumatic Acid is a monounsaturated dicarboxylic acid isolated from  Phaseolus vulgaris. Traumatic Acid can cause a decrease in membrane phospholipid peroxidation and show antioxidant and stimulatory effects on collagen biosynthesis. Traumatic Acid is a potential agent for the treatment of many skin diseases connected with collagen biosynthesis disorders and oxidative stress.
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DC67928 Tetracosanal Featured
DC67927 N-Tetracontane Featured
N-Tetracontane is an ester product.
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DC67926 Heptacosane Featured
Heptacosane is an ester product.
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DC67925 3-Hydroxytetradecanoic acid Featured
3-Hydroxytetradecanoic acidis a saturated fatty acid. 3-Hydroxytetradecanoic acidOccurs naturally in various animal and plant sources such as butter and milk fat. 3-Hydroxytetradecanoic acidIt has various uses in industry, especially in the production of soaps, detergents and other surfactants. 3-Hydroxytetradecanoic acidIt is also used as a precursor for the synthesis of other bioactive compounds such as antibiotics and anticancer drugs.
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DC67924 16-Heptadecenoic acid Featured
DC67923 16-bromohexadec-1-ene Featured
DC67922 10E-Hexadecen-1-ol Featured
DC67921 Pentatriacontane Featured
Pentatriacontane is an ester product.
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DC67920 (E)-10-Hexadecenal Featured
(E)-10-Hexadecenal is a pheromone that can be isolated from the fruit-feeding type of yellow peach moth, Dichocrocis punctiferalis.
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DC67919 (9Z)-Dodecen-1-ol Acetate Featured
DC67918 10-Hexadecen-1-ol, acetate, (Z)- Featured

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