Cyclophilin inhibitor, showing reduction in interleukin-2 expression and reduction in CNS inflammatory infiltrates, inhibiting HCoV-229E replication

Potent and selective NOP receptor antagonist

Novel fluorescent probe for imaging α4β2* nAChRs

Antilipidemic agent

Novel inhibitor of the sterol regulatory element binding protein (SREBP)

Selective Inhibitor of Human Lactate Dehydrogenase Isoform A (LDH-A)

UAMC1110 Conjugate Linker

Novel luciferin analog, enabling both sensitive and highly resolved imaging in vivo

Novel cell-permeant probe for the super-resolution imaging of the endoplasmic reticulum in live cells

Brain-permeable dual blocker of neuronal voltage- and ligand-operated calcium channels, acting as chemosensitizer and circumvent the resistance of the plasmodia parasite against chloroquine (CQ) by inhibiting the p-glycoprotein efflux pump and enabling th

New generation, topology 2 selective corticotropin releasing factor-1 (CRF-1) receptor antagonist

Novel TRPV1 Antagonist

New generation, topology 2 selective orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist

Novel inhibitor of human cytomegalovirus (HCMV) infection

Neutrophil Dysfunction Test Peptide

First-in-class inhibitor of NF-κB signaling pathway by preventing the maturation of a rate-limiting multiprotein complex necessary for IKK activation

Inhibitor of NFAT-mediated transcription, leading to the suppression of interleukin-2 expression and T cell proliferation, showing immunosuppressive, antidiabetic, and antitrypanosomal activities

Novel potent HDAC6 degrader with promising antiproliferation activity in multiple myeloma (MM) cells

The neurotensin active fragment, eliciting behavioral responses typical of clinically used antipsychotic drugs when administered directly to the brain

Novel neuroprotectant for Alzheimers disease, showing significant neuroprotection and antioxidative properties, crossing the blood-brain barrier (BBB)

Novel neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons

Novel inhibitor of TbrPDEB1, showing modest inhibition of T. brucei proliferation

Novel inhibitor of the growth of protozoan parasites, against T. brucei bloodstream proliferation

Novel potent Trypanosoma brucei Inhibitor

Ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth

Modulator of the T1007 site, resulting in rapid activation of this transporter and potentiating KCC2 activity

Lidocaine metabolite, showing antinociceptive effects, inhibiting GlyT1-mediated glycine uptake

Novel fluorescent RXR antagonist

Novel dual Rho Kinase and norepinephrine transporter (ROCK/NET) inhibitor

Anti-inflammatory, antibronchospastic agent