Novel inhibitor of mitochondrial respiration, targeting drug-resistant cancer cells with stem-like features by inhibiting mitochondrial respiration complex I (NADH:ubiquinone oxidoreductase, complex I [CI])

Novel Hsp90 inhibitor

Potent Androgen_receptor>androgen receptor (AR) pure antagonist which did not produce the agonist metabolite

Novel Hsp90 inhibitor

Novel microtubule polymerization inhibitor with little susceptible to transporter-mediated chemoresistance

Novel Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitor

The first small-molecule based MCM2-targeted NIR-II probe

Benzodiazepine receptor partial agonist

Benzodiazepine antagonist

Water soluble CycLuc3, mutant firefly luciferase variant with enhanced light emission

Matrix metalloproteinase (MMP) inhibitor

Mutant firefly luciferase variant with enhanced light emission

Broad spectrum matrix metalloproteinase (MMP) inhibitor

Liver specific thyromimetic agonist of thyroid hormone receptor-

Peptoid Tat/transactivation response element inhibitor, inhibiting human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry

Novel HIV-1 protease inhibitor, also potently inhibiting major aspartyl peptidase 1 (May1), a secreted Cryptococcus neoformans protease

Activator of RORalpha, inducing growth arrest in androgen-independent DU 145 prostate cancer cells

Non-peptide tachykinin NK1 receptor antagonist

Novel inhibitor of Wnt/β-catenin signaling; Anticancer agent promoting PKCα-mediated β-catenin phosphorylation/degradation

Novel Bruton's tyrosine kinase (BTK) inhibitor

Novel functional Gboxin analogue that is suitable for live-cell ultraviolet crosslink conjugation and click chemistry

Novel PRL-3 inhibitor, blocking the migration and invasion of metastatic cancer cells

Novel inducer of neural differentiation and growth arrest in human primary GBM-derived cells, playing a tumor-suppressive role via cAMP/CREB signaling pathway

Novel GSK3 inhibitor, inducing cell death through cyclin D1 depletion in breast cancer cells

Novel Highly Potent, Selective, Bioavailable TTK (threonine tyrosine kinase) Inhibitor

Potent inhibitor of TTK kinase

Novel non-steroid reversible dual inhibitor of CYP17 and CYP11B2 against prostate cancer with fewer cardiac side effects

Novel Probe for the High Temperature Requirement A (HTRA) Serine Proteases

Novel probe for cellulose synthase trafficking, inhibiting cellulose deposition and interferes with the trafficking of cellulose synthase complexes and their associated proteins KORRIGAN1 and POM2/CSI1

Novel small molecule prodrug for use with SEAKER cells, exhibiting enhanced anticancer activity