Zopolrestat is a aldose reductase inhibitor potentially for the treatment of diabetic nephropathy and diabetes.

Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1). Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism. Zoniporide produces clinical, electrophysiologic, and microscopic evidence of peripheral sensory axonopathy and establishes the importance of careful preclinical evaluation of neurological function.

Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x more potent as an estrogen agonist than the related compound zearalenone. Zeranol increases cancer cell proliferation in already existing breast cancer. There are mixed results to whether zeranol has anticancer or carcinogenic properties in non cancer containing breast cells depending on dose. Overall evidence points to zeranol being a risk factor and promoter for cancer. However, dietary exposure from the use of zeranol-containing implants in cattle is insignificant.

Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats.

Way 100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist, and was originally believed to be highly selective, but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A), and to a much lesser extent, of the 5-HT1B receptor (pKi = 5.82). These findings may have prompted the development of the related compound WAY-100,635, another purportedly selective and even more potent 5-HT1A antagonist, which was synthesized shortly thereafter.

Vibunazole is an antifungal agent

KUN79359, also known as PKC? inhibitor, is a potent and selective inhibitor of PKC? isozymes. KUN79359 has no formal name, and has CAS#257879-35-9. For the convenience of scientific communication, it is named as KUN79359. The name was generated based on Hodoodo chemical nomenclature.

Triflumuron is an insecticide belonging to the group of so-called insect growth regulators. It inhibits the synthesis of chitin by the insect larvae, causing the die. This operation is similar to that of, inter alia, flufenoxuron , lufenuron and novaluron ; triflumuron belongs to the same group of benzoylureas. It is a product of Bayer CropScience ; Alsystin brand. It is applied to apples, pears, peaches, nectarines and mushrooms, as well as in the storage of cereals.

Triadimenol is a flammable white to gray solid with phenolartigem odor which is practically insoluble in water. It decomposes when heated above 150 ° C. The compound is present in several isomeric front forms, the technical product to 78 to 88% of the diastereoisomer A is (RS + SR). The compound is stable to hydrolysis at pH values ??of 4, 7 and 9 and is subject to a small extent of photolysis. Triadimenol is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis , and thus the rate of cell division.

SKF1 is a suppressor of the ability of FK506 to inhibit cell growth in the presence of high levels of NaCl, inducing cell death in low salt conditions, interacting directly with yeast mitochodria.

Triadimefon is an azole fungicide.

TMI-1 is a novel orally active inhibitor of ADAM17 (TACE) and MMP, inducing tumor apoptosis in a breast cancer.

Tomelukast, also known as LY171883, is a leukotriene inhibitor. Tomelukast showed protective effects in traumatic shock. LY-171883 stimulates the activity of BK(Ca) channels in a manner unlikely to be linked to its blockade of leukotriene receptors or stimulation of peroxisome proliferator-activated receptors. The stimulatory effects on these channels may, at least in part, contribute to the underlying cellular mechanisms by which LY-171883 affects neuronal or neuroendocrine function.

MAFP is an irreversible inhibitor of Ca(2+)-independent phospholipase A2 (iPLA2).

Proxyfan Oxalate is a potent histamine H3 receptor ligand, acting as a protean agonist with activity ranges from full agonist to inverse agonist depending on system used. also displaying partial agonist effects on cAMP inhibition and MAPK activity, neutral antagonist activity on histamine release and partial inverse agonism of [3H]-arachidonic acid release.

Thiolactomycin is a novel reversible dual inhibitor of D-Aspartate oxidase (DDO) and D-amino acid oxidase (DAO).

Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi. Though the U.S. Food and Drug Administration considers this fungicide to be safe for humans, it may still pose a risk. It is listed as a possible carcinogen in the United States Environmental Protection Agency Office of Pesticide Programs carcinogen list with a rating of C (possible carcinogen). Its acute toxicity is moderate. According to the World Health Organization toxicity classification, it is listed as III, which means slightly hazardous.

AZ-PFKFB3-67 is a novel potent and selective PFKFB3 inhibitor.

Z-LLNle-CHO, also known as gamma-Secretase Inhibitor I, is a cell permeable inhibitor of gamma-secretase, inducing apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.

FKGK11 is a novel potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively).

HUN85199, also known as B-Raf inhibitor 1 dihydrochloride, is a novel potent and selective B-Raf inhibitor. HUN85199 has CAS#1191385-19-9, was first reported in Journal of Medicinal Chemistry (2009), 52(20), 6189-6192. It has no code name. For the convenience of scientific communication, we name it as HUN85199 by using CAS# ahdn inchi key as proposed by Hodoodo Chemical Nomenclature (see https://hodoodo.com/hodoodo-chemical-nomenclature).

Sulbactam pivoxil, also known as CP-47904 and Pivsulbactam, is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic.

Sudoxicam is a nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.

Sulfamonmethoxine is a competitive inhibitor of dihydropteroate synthetase, blocking the synthesis of folic acid.

MHY908 is a novel inhibitor of melanogenesis, potently inhibiting mushroom tyrosinase activity in a dose-dependent manner.

CP-944629 is a novel, potent, and selective p38alpha inhibitor.

BMS-770767 is a novel inhibitor of 11-betahydroxysteroid dehydrogenase type I (11?-HSD1).

Sofalcone is an oral gastroprotective, gastrointestinal medication. It is a synthetic analog of sophoradin.

HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.

Pyrabactin is a plant growth inhibitor, acting as a seed-selective abscisic acid (ABA) agonist; Novel PYL agonist.