Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission.

CTP inhibitor; Inhibitor of the mitochondrial citrate transport protein;

FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety.

modulating CFTR activity; restore E-cadherin expression in the SW620 colon adenocarcinoma cell line; altering the lifespan of a eukaryotic organism;

microRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. microRNA-21-IN-2 can be used for the research of cancer.

Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments.

BRD 4354 is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively.

Pin1 ligands; Mycobacterium tuberculosis shikimate kinase inhibitors;

altering the lifespan of a eukaryotic organism; PfENR inhibitor;

11β-hydroxysteroid dehydrogenase type I modulator; sodium channel inhibitors.

serine/threonine kinase inhibitors

SIRT2-IN-9 (compound 12) is a selective inhibitor of SRIT2 with an IC50 value of 1.3 μM. SIRT2-IN-9 inhibits proliferative activity of MCF-7 breast cancer cells. SIRT2-IN-9 can be used for the research of cancer.

Inhibitors of Glutathione S-Transferase Omega 1

increasing ion transport by mutant-CFTR; altering the lifespan of a eukaryotic organism;

altering the lifespan of a eukaryotic organism; inhibitor of protein kinases;