Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC1009 | Laropiprant Featured |
MK 0524 is a potent, selective DP1 receptor antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively.
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DC8111 | Idarubicin Hydrochloride Featured |
Idarubicin Hcl is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor.
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DC21584 | MIN-101 Featured |
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia..
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DC65793 | 1,2-Di(cis-13-docosenoyl)-sn-glycero-3-phosphoethanolamine |
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DC7923 | TAK-599 (ceftaroline fosamil) Featured |
TAK-599 is a highly promising parenteral cephalosporin targeted for MRSA infection.
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DC65764 | 14:0 PEG2000 PE Featured |
14:0 PEG2000 PE (DMPE-PEG2000) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier.
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DC8029 | ANA-12 Featured |
ANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.
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DC70796 | SRI-41315 Featured |
SRI-41315 is a small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion, restores CFTR expression and function, suppresses CFTR nonsense mutations.SRI-41315 induces translational readthrough by depleting eRF1 protein level and prolonging the translational pause that occurs at premature termination codons (PTCs).SRI-41315 reduced eRF1 levels in a manner dependent upon a ubiquitin-mediated proteasome degradation pathway.SRI-41315 in combination with G418 restores CFTR function in primary bronchial epithelial cells derived from a CF patient with CFTR nonsense alleles.
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DC71316 | MC2652 Featured |
MC2652 (compound 1a) is a potent LSD1 inhibitor. MC2652 displays high inhibiting effects in MV4-11 and NB4 leukaemia cells. MC2652 shows antiproliferative activity against prostate cancer LNCaP cells.
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DC65734 | 1-Palmitoyl-2-(propargylacetyl)-sn-glycero-3-phosphocholine |
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DC72663 | SW222746 Featured |
SW222746 (SW 222746) is a potent selective, orally active inhibitor of 15-Prostaglandin dehydrogenase (15-PGDH) with IC50 of 3 nM.
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DC65724 | 1-Stearoyl-sn-glycero-3-phosphocholine Featured |
1-Stearoyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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DC7942 | ML-265 Featured |
ML-265 activates tumor-specific PKM2 (EC50 = 92 nM) by binding to the dimer-dimer interface between two subunits of PKM2 and inducing tetramerization.
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DC41224 | Minoxidil sulfate Featured |
Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo.
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DC31690 | Finasteride Featured |
Finasteride is a medication used for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). It is a type II and type III 5α-reductase inhibitor; 5α-reductase, an enzyme, converts testosterone to dihydrotestosterone (DHT).
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DC46502 | Brilacidin Featured |
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound.
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DC8067 | Cefozopran Featured |
Cefozopran (SCE-2787) is a new parenteral cephalosporin, against experimental infections in mice.
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DC9188 | Liothyronine sodium Featured |
Liothyronine sodium (T3 Sodium sal) is the most potent form of thyroid hormone used to treat hypothyroidism and myxedema coma.
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DC12189 | γ-L-Glutamyl-L-alanine Featured |
γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins.
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DC10296 | Glutamylphenylalanine Featured |
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth.
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DC9005 | (S)-(+)-ketoprofen Featured |
Dexketoprofen works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).
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DC23502 | L-AP4 Featured |
L-AP4 is a selective group III metabotropic glutamate receptor agonist..
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DC41139 | D-4-Hydroxyphenylglycine Featured |
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin and Cefadroxil.
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DC23510 | LY2794193 Featured |
LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor..
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DC7148 | LY 379268 Featured |
Highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors.
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DC26045 | Semax Featured |
Semax is a synthetic peptide analog of adrenocorticotropic hormone
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DC2014 | Flavopiridol Featured |
Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM, and CDK7 with IC50 of 300 nM.
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DC28200 | LY367385 Featured |
LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 μM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects.
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DC60324 | WAY-622024 Featured |
WAY-622024(Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders.
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DC10364 | (±)-Pirmenol Featured |
Pirmenol inhibits IK.ACh by blocking muscarinic receptors. The IC50 of Pirmenol for inhibition of Carbachol-induced IK.ACh is 0.1 μM.
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