The neurotensin active fragment, eliciting behavioral responses typical of clinically used antipsychotic drugs when administered directly to the brain

Novel neuroprotectant for Alzheimers disease, showing significant neuroprotection and antioxidative properties, crossing the blood-brain barrier (BBB)

Novel neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons

Novel inhibitor of TbrPDEB1, showing modest inhibition of T. brucei proliferation

Novel inhibitor of the growth of protozoan parasites, against T. brucei bloodstream proliferation

Novel potent Trypanosoma brucei Inhibitor

Ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth

Modulator of the T1007 site, resulting in rapid activation of this transporter and potentiating KCC2 activity

Lidocaine metabolite, showing antinociceptive effects, inhibiting GlyT1-mediated glycine uptake

Novel fluorescent RXR antagonist

Novel dual Rho Kinase and norepinephrine transporter (ROCK/NET) inhibitor

Anti-inflammatory, antibronchospastic agent

Human B-type natriuretic peptide, facilitating cardiovascular fluid homeostasis through counterregulation of the renin-angiotensin-aldosterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation

Novel non-peptidic, non-covalent cruzain inhibitor

The first potent NAD-driven small molecular inhibitor of TcGAPDH (Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase)

Novel AR inhibitor, being selective for the testosterone stimulated AR-dependent prostate cancer cell

Natural inducer of autophagy and apoptosis, inhibiting glutamate overexcitation and upregulation of the Wnt/β-catenin signaling pathway

Potent natural anti-tumor agent against metastatic colorectal cancer, resulting in cell cycle arrest at the G2/M phase and inducing apoptosis through the dysfunction of mitochondria to trigger intrinsic apoptotic pathway by untargeted metabolomic method,

Inhibitor of the formation of

Natural inhibitor of tumor metastasis by upregulating the RNA-binding-protein MBNL2, inducing cell cycle arrest through multiple signaling pathways including RNA binding protein CELF6

Novel ATP-competitive inhibitor of Nek2 and Nek7

Novel Inhibitor of DNA Glycosylases, inhibiting NEIL1 activity

Non-narcotic analgesic for the relief of acute and chronic pain

Novel inhibitor of caspase-independent cell death with necrotic morphol, distinctly different from apoptosis, autophagy, and necroptosis, displaying strong mitochondrial reactive oxygen species and ONOO- scavenging activity

Novel necroptosis inhibitor

Negative control compound for Necrostatin-1 related assays

Novel Inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1)

Novel G4-DNA ligand, promoting transcription in Gram-positive bacteria and repressing transcription in Gram-negatives

Major metabolite of loperamide, also used as the precusor for radiolabelled loperamide

Precursor for radiolabeled diltiazem