Novel irriversable serine hydrolases inhibitor

Novel potent inhibitor of Mpro

Covalent dual inhibitor of DPAP1 and DPAP3

Covalent dual inhibitor of DPAP1 and DPAP3

Novel dose-dependent inhibitor of ABHD6

Negative control of JCP174

JCP174 analog used for affinity purification of labeled targets

Novel dose-dependent inhibitor of ABHD6

Novel RORα activator, diminishing diethylnitrosamine-induced acute liver injury and repressing transcriptional expression of APPs such as CXCL1 and LCN2 in mice

Metabolite of JBSNF-000088

Natural anti-inflammatory agent, showing potential for the treatment of inflammatory bowel disease (IBD)

Inhibitor of renal transporters OAT1 and OAT3; Antihepatitis agent as a substrate for intestinal PEPT1

Natural radical scavenger, inhibiting L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells

Natural Inhibitor for Protein−Protein Interaction of the Homodimer of Proteasome Assembly Factor 3

Potent inhibitor of the proliferation of PC3 prostate carcinoma cells

Natural naphthyridine alkaloid

Novel Inhibitor of Jumonji AT-Rich Interactive Domain 1B (JARID1B) Histone Demethylase

Novel mitophagy inducer with therapeutic potential for Parkinson's disease, acting as light chain 3 (LC3) interactors, similar to cardiolipin or ceramide, triggering mitophagy via Pink1/Parkin

Novel fluorogenic yellow fluorescent dye for use in self-labeling tag systems

Novel anti-triple-negative breast cancer (anti-TNBC) agent with a high selectivity against BC cells over normal human cells, downregulating phosphatidylinositide 3-kinase (PI3K)/Akt pathway by suppressing protein-tyrosine phosphatase 1B (PTP1B) expression

Novel positive allosteric modulator of AMPA receptor

Novel potent JAK1/3 inhibitor, targeting JAK3 and JAK1 with IC 50 at 3nM and 5nM, respectively

Novel potent JAK1/2/3 inhibitor

Novel Selective JAK3 Inhibitor with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Novel Selective JAK3 Inhibitor with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Novel irreversible selective JAK3 inhibitor through the covalent interaction with a Jak3 active-site cysteine

Novel irreversible selective JAK3 inhibitor through the covalent interaction with a Jak3 active-site cysteine

Novel irreversible selective JAK3 inhibitor through the covalent interaction with a Jak3 active-site cysteine

Novel selective Jak2 inhibitor, demonstrating a time-dependent knock-down of pSTAT5, a downstream target of Jak2

Novel JAK1 inhibitor