Novel potent inhibitor of heat shock protein 90 (Hsp90), effectively reducing the expression levels of Hsp90 client proteins including Her2, EGFR, Met, Akt, and c-Raf

Novel Hsp90-Aha1 chaperone complex formation inhibitor, enhancing F508del-CFTR channel activity

Novel inhibitor of heat shock 27 kDa protein (HSP27), significantly inducing AR degradation in GBM cells via the proteasomal pathway, selectively inhibiting AR-overexpressed GBM cell growth with IC 50 values around 5 nM

Novel Peripherally-Restricted Kappa Opioid Receptor (KOR) Agonist with Antinociceptive and Antipruritic Effects

Novel inhibitor of lipoteichoic acid (LTA) biosynthesis, potently inhibiting S. aureus and E. faecalis growth and biofilm formation

Novel potent inhibitor of the recombinant FLT3 kinase and its mutant forms, blocking the proliferation of AML cell lines, harboring oncogenic FLT3-ITD mutations with remarkable IC50 values, which were comparable to the approved FLT3 inhibitor quizartinib,

Novel anticancer Gold(III) agent with remarkable cytotoxicity to gastric cancer cells

μ-Opioid Receptor Agonist

Novel inhibitor of imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia

Inhibitor of human rhinoviruses serotype 14 (HRV-14)

Novel Probe of the hras-1Y i-motif , selectively and directly interacting with the hras-1Y i-motif.

Loxoprofen active metabolite, acting as a safe intravenous NSAID with superior anti-inflammatory and analgesic activities

Novel silanol-based human pregnane X receptor (PXR) agonist

Novel highly selective switch-on fluorescence sensor, targeting telomeric dimeric G-quadruplex, discriminating the telomeric dimeric G-quadruplex TTA45 against other types of DNA structures accompanied by a drastic enhancement of the emission intensity wi

Novel c-Met inhibitor, markedly reducing tumor growth, showing excellent pharmacodynamics, and suppressing cell proliferation and microvessel density in an orthotopic model of triple negative breast cancer

Histamine H1 receptor antagonist

Natural inhibitor of dietary fat absorption and showing strong anti-obesity activity

Antibiotic

Novel specific Aurora B inhibitor

Fluorescent indicator of apoptosis, binding the minor groove of DNA at A and T rich regions

Highly potent and selective ligand for the GHB binding sites, binding with 27 times better affinity than GHB itself and acrossing the blood brain barrier in vitro and in vivo

Novel strobilurin acaricide, exhibiting larvicidal and ovicidal activities against various acarids

Novel selective inhibitor of the lymphocytic leukemia (LL) cell survival , Selectively Enhancing the Killing Effect through STAT3 Binding on Lymphocytic Leukemia Cells In Vitro and In Vivo

Novel Blinking Fluorescent Probe for Tubulin Nanoscopy in Living and Fixed Cells

Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing

Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing

Novel Hexosaminidase-Targeting Fluorescence Probe for Visualizing Human Colorectal Cancer.

Novel sialidase-activatable fluorescence probe with improved stability for the sensitive detection of sialidase

Potent and selective I ks channel blocker

Novel food intake-reducing agent