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PROTACs

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Cat. No. Product Name Field of Application Chemical Structure
DC48798 Cbz-PEG5-Br
Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48790 Lenalidomide-C5-NH2 TFA
Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs, such as MDM2 PROTAC degrader.
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DC48729 Triethylene glycol monododecyl ether
Triethylene glycol monododecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48728 Br-PEG6-CH2COOtBu
Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48701 t-Boc-N-amido-PEG5-acetic acid
BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48700 Bromo-C4-PEG4-t-butyl ester
Bromo-C4-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48677 Bromo-PEG7-amine
Bromo-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48673 Bromo-PEG5-CH2COOtBu
Bromo-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48653 t-Boc-Aminooxy-PEG4-amine
t-Boc-Aminooxy-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48652 t-Boc-N-amido-PEG2-C6-Cl
t-Boc-N-amido-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48618 Amino-PEG6-acetic acid
Amino-PEG6-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48615 Iodo-PEG7-alcohol
Iodo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48607 Cbz-PEG2-bromide
Cbz-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48588 Benzyl-PEG3-amine
Benzyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48584 Mal-amido-PEG3-alcohol
Mal-amido-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48504 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride
2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48458 L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride
L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48440 m-PEGn-NHS ester
m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48432 tert-Butyl 11-aminoundecanoate
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker that refers to the PEG composition. tert-Butyl 11-aminoundecanoate is applicable to the synthesis of a series of PROTACs.
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DC48429 Di(N-succinimidyl) adipate
Di(N-succinimidyl) adipate (DSAP) is an alkyl chain-based PROTAC linker that is applicable to the synthesis of PROTACs.
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DC21893 dBET57 Featured
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM), but is inactive on BRD4 BD2..
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DC26119 VHL ligand 2 hydrochloride Featured
VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader.
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DC39709 Lenalidomide-Br Featured
Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs.
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DC28671 DT2216 Featured
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC). DT2216 targets BCL-XL to the Von Hippel-Lindau (VHL) E3 ligase for degradation. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets.
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DC39826 Homo-PROTAC cereblon degrader 1 Featured
Homo-PROTAC cereblon degrader 1, is a cereblon degrader.
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DC11575 E3 Ligand-Linker Conjugate 9 Featured
An E3 ligase ligand-linker conjugate for PROTAC.
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DC11572 E3 Ligand-Linker Conjugate 6 Featured
An E3 ligase ligand-linker conjugate for PROTAC..
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DC11573 E3 Ligand-Linker Conjugate 7 Featured
An E3 ligase ligand-linker conjugate for PROTAC..
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DC11565 E3 Ligase Ligand 2 Featured
E3 ligase Ligand 2 is a Ligand for E3 Ligase used in PROTAC technology.
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DC12380 BSJ-03-123 Featured
BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC) that uniquely enables rapid pharmacological interrogation of CDK6-dependent functions.
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