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PROTACs

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Cat. No. Product Name Field of Application Chemical Structure
DC49197 PROTAC BRD9 Degrader-2
PROTAC BRD9 Degrader-2 is a BRD9 bifunctional degrader for treating cancer.
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DC49196 Pomalidomide-C5-Dovitinib
Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC containing Pomalidomide, Dovitinib and connected with CRBN. Pomalidomide-C5-Dovitinib shows enhanced antiproliferative effects against FLT3-ITD+ AML cells. Pomalidomide-C5-Dovitinib induces the degradation of the FLT3-ITD and KIT proteins in a ubiquitin-proteasome-dependent manner and completely blocks their downstream signaling pathway. Pomalidomide-C5-Dovitinib has the potential for the research of FLT3-ITD+ acute myeloid leukemia.
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DC49195 m-PEG18-acid
m-PEG18-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49184 t-Boc-N-amido-PEG15-Br
t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49183 Biotin-PEG10-NHS ester
Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49178 HO-PEG18-OH
HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49176 Acid-PEG14-t-butyl ester
Acid-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49166 N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)
N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49154 m-PEG15-acetic acid
m-PEG15-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49144 Acid-PEG12-t-butyl ester
Acid-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49143 Biotin-PEG10-amine
Biotin-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49115 Biotin-PEG9-amine
Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49098 t-Boc-Aminooxy-PEG11-amine
t-Boc-Aminooxy-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49097 Biotin-PEG6-NH-Boc
Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49083 PROTAC-O4I2
PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 (SF3B1). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells.
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DC49079 Acid-PEG10-t-butyl ester
Acid-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49049 t-Boc-N-amido-PEG10-Br
t-Boc-N-amido-PEG10-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49048 t-Boc-amido-PEG10-acid
t-Boc-amido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49017 Dodecylheptaglycol
Dodecylheptaglycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC49015 Acid-PEG9-t-butyl ester
Acid-PEG9-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48989 Amino-PEG11-acid
Amino-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48988 N-Boc-PEG10-alcohol
N-Boc-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48932 Bis-PEG4-TFP ester
Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48914 FmocNH-PEG3-CH2CH2NH2 hydrochloride
FmocNH-PEG3-CH2CH2NH2 (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48882 Bromo-PEG8-CH2COOtBu
Bromo-PEG8-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48879 Acid-PEG7-t-butyl ester
Acid-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48849 Boc-NH-PEG7-acetic acid
Boc-NH-PEG7-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48839 Fmoc-PEG3-alcohol
Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48802 t-Boc-Aminooxy-PEG4-t-butyl ester
t-Boc-Aminooxy-PEG4-t-butyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC48801 Bromo-PEG7-CH2COOtBu
Bromo-PEG7-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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