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Homo-PROTAC cereblon degrader 1

  Cat. No.:  DC39826   Featured
Chemical Structure
2244520-98-5
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More than 5000 active chemicals with high quality for research!
Field of application
Homo-PROTAC cereblon degrader 1, is a cereblon degrader.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2244520-98-5
Chemical Name: Homo-PROTAC cereblon degrader 1
Synonyms: Homo-PROTAC cereblon degrader 1
SMILES: O=C1C([H])(C([H])([H])C([H])([H])C(N1[H])=O)N1C(C2C([H])=C([H])C([H])=C(C=2C1=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C2C(N(C(C=21)=O)C1([H])C(N([H])C(C([H])([H])C1([H])[H])=O)=O)=O)=O
Formula: C32H32N6O10
M.Wt: 660.630687713623
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3[1].
Target: Celeblon[1].
References: [1]. Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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