Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC11064 | BTK PROTAC 9 |
BTK PROTAC 9 is a novel potent PROTAC for BTK with DC50 of 5.9 nM in cultured Ramos cells, requires simultaneous engagement of BTK and CRBN to effectively degrade BTK.
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DC11065 | BTK PROTAC 10 |
BTK PROTAC 10 is a novel potent PROTAC for BTK with DC50 of 1.1 nM in cultured Ramos cells.
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DC10997 | BRD4 degrader AT1 |
BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells.
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DC11567 | BETd-260 trifluoroacetate |
BETd-260 trifluoroacetate (ZBC260, BETd 260 TFA) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL.
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DC11569 | E3 Ligand-Linker Conjugate 4 |
An E3 ligase ligand-linker conjugate for PROTAC...
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DC11576 | E3 Ligand-Linker Conjugate 10 |
An E3 ligase ligand-linker conjugate for PROTAC..
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DC11563 | E3 Ligand-Linker Conjugate 2 |
An E3 ligand- Linker Conjugate for PROTAC..
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DC11580 | VHL-2 |
A VHL ligand for PROTAC..
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DC11581 | VHL Ligand 4 |
A VHL ligand for PROTAC..
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DC11582 | N3-PEG4-CH2COOH |
A PEG4 linker for PROTAC..
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DC11577 | N3-PEG3-CH2COOH |
A PEG3 linker for PROTAC..
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DC11583 | N3-PEG2-CH2COOH |
A PEG2 linker for PROTAC..
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DC11593 | Bis-PEG6-acid |
A PEG linker for PROTAC..
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DC11592 | Bis-PEG5-acid |
A PEG linker for PROTAC..
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DC11591 | Bis-PEG4-acid |
A PEG linker for PROTAC..
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DC11562 | Sirt2-PROTAC-1 |
A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM)..
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DC11867 | TBK1 PROTAC 1 |
A novel potent, selective TBK1 PROTAC with DC50 of 12 nM, selectively degrades TBK1 with excellent selectivity against a related kinase IKKε.
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DC11564 | CDK9-PROTAC |
A heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9.
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