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| Cas No.: | 2244989-34-0 |
| Chemical Name: | 3-(3,4-Difluorophenyl)-N-[(1S)-1-[6-(4-pyridin-2-ylpiperazin-1-yl)pyrazin-2-yl]ethyl]propanamide |
| Synonyms: | Benzenepropanamide, 3,4-difluoro-N-[(1S)-1-[6-[4-(2-pyridinyl)-1-piperazinyl]-2-pyrazinyl]ethyl]-;3-(3,4-Difluorophenyl)-N-[(1S)-1-[6-(4-pyridin-2-ylpiperazin-1-yl)pyrazin-2-yl]ethyl]propanamide;(-)-(S)-B-973B |
| SMILES: | FC1=C(C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C(N([H])[C@@]([H])(C([H])([H])[H])C1=C([H])N=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])=O)F |
| Formula: | C24H26F2N6O |
| M.Wt: | 452.4997 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | (-)-(S)-B-973B is a potent allosteric agonism and positive allosteric modulation (ago-PAM) for α7 nAChR, with antinociceptive activity[1]. |
| References: | [1]. Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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