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Cat. No. Product Name Field of Application Chemical Structure
DC10636 SC75741 Featured
SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
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DC9273 SC-66 Featured
SC-66 is an allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination.
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DC7281 SC-514 (GK 01140) Featured
SC-514 (GK 01140), a small molecule, is a selective inhibitor of IKK-2; does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.
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DC39262 SBP-7455 Featured
SBP-7455 is an orally active dual-specific ULK1/2 autophagy inhibitor with improved binding affinity compared with SBI-0206965.
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DC8316 SBI-0206965 Featured
SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor.
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DC10148 SBC-110736 Featured
SBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), lowering cholesterol levels in mice.
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DC10729 SB9200(Inarigivir soproxil) Featured
SB9200(Inarigivir soproxil) is a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants.
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DC8354 Intepirdine (SB-742457, RVT-101) Featured
SB-742457(RVT-101) is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.
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DC9635 SB-705498 Featured
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1.
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DC7279 SB-590885 Featured
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.
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DC6312 SB525334 Featured
SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.
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DC7278 SB-505124 Featured
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.
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DC7670 SB-3CT Featured
SB-3CT is an effective and selective gelatinase inhibitor with Ki of 13.9 nM and 600 nM for MMP-2 and MMP-9, respectively.
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DC9735 SB-366791 Featured
SB-366791 is a selective and competitive VR1 (TRPV1) antagonist that is commonly used in pain research.
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DC1004 SB-203580 Featured
SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM.
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DC7493 SB1317(TG-02) Featured
SB1317(TG-02) is a novel small molecule potent CDK2/JAK2/FLT3 inhibitor with IC50s of 13/73/56 nM respectively.
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DC9459 SB 415286 Featured
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.
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DC7807 SB 239063 Featured
SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580.
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DC4227 SB216763 Featured
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
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DC2097 SB202190 Featured
SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway.
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DC8875 Saxagliptin Featured
Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM.
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DCAPI1568 Saxagliptin Hydrochloride Featured
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs.
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DC9692 Volitinib(Savolitinib) Featured
Savolitinib(Volitinib; AZD-6094; Volitinib) is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase(IC50= 5 nM) with potential antineoplastic activity.
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DC9313 Sarpogrelate (hydrochloride) Featured
Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
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DC9854 SAR407899 Featured
SAR407899 is a potent, ATP-competitive ROCK inhibitor woth Ki value of 36 nM/41 nM for human ROCK/Rat ROCK respectively.
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DC10823 SAR-20347 Featured
SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.
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DC8530 SAR131675 Featured
SAR131675 is a potent and selective VEGFR-3 inhibitor.
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DC8224 Lifitegrast(SAR 1118) Featured
SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye.
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DC8327 SANT-1 Featured
SANT-1 is a membrane permeable antagonist of the Shh (Sonic Hedgehog) signaling pathway by direct binding to Smo.
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DCAPI1177 Salubrinal Featured
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM.
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