An orally bioavailable, highly potent and selective pan-class I phosphatidylinositol-3 kinase (PI3K) inhibitor

Novel selective PPARγ modulator (sPPARγM), potently inhibiting CDK5-mediated PPARγ phosphorylation and displaying a selective gene expression profile in epididymal WAT

Novel irreversible transglutaminase 2 (TG2) inhibitor

Novel potent and selective inhibitor of mitochondrial respiration supported by pyruvate

Marine cyanobacterium-derived natural antimalarial agent; Potent Inhibitor of the Food Vacuole Falcipains

An isomeric anlog of G140 (AOB13353), acting as an inhibitor of h-cGAS (IC 50 = 0.0428µM)

Novel clickable, electrophilic diazene probe, enabling capture and site-centric proteomic analysis of oxidative post-translational modification (OxiPTM)

Novel agonist of STING (stimulator of interferon genes) with enhanced binding to STING and cellular function

H1-histamine receptor blocker, antiarrhythmic

Novel second-generation SIK inhibitor, inducing not only synthesis of melanin but also melanosomal maturation, export, and localization features, even after import into keratinocytes

Novel inhibitor of ER-to-cytosol protein dislocation, exhibiting anti-dengue and anti-Zika virus activity

The first small molecule modulator of cold inducible RNA-binding protein (CIRBP) activity

The first small molecule modulator of cold inducible RNA-binding protein (CIRBP) activity

Novel potent and selective SMS2 inhibitor, showing more than 1400-fold selectivity over SMS1

Novel immune checkpoint VISTA (V-domain immunoglobulin suppressor of T-cell activation) modulator

Potent and selective inhibitor of Galactokinase (GALK)

Highly potent κ agonist

A novel potent and selective negative modulator of AMPA receptors containing TARP-gamma8

Novel selective GPR120 agonist

Novel neuroprotective agent, significantly reducing Aβ toxicity by delaying paralysis and improving cognitive performances in a transgenic mouse model of AD

Novel activator of SIRT6 deacetylation

Inhibitor of CBFβ-RUNX protein-protein interaction

Activator of calcium receptor; Flavor-enriching agent

Selective Myosin-1 (Myo1) inhibitor, suppressing transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells

Novel potent AfNMT inhibitor, potently inhibiting the NMT mutant and being fungicidal under repressed nmt expression

Novel potent AfNMT inhibitor, potently inhibiting the NMT mutant and being fungicidal under repressed nmt expression

Fluorescent indicator for detecting the interaction between RNA and a ligand

A CDK, JAK and FLT inhibitor

Inhibitor of KIAA1363 (or AADACL1)

Selective GPR35 antagonist