Novel allosteric PTP4A3 inhibitor, increasing Emilin 1 gene expression

Novel potent auxin antagonist

Novel specific inhibitor of bacterial RecBCD helicase-nuclease DNA repair enzyme; Inhibitor of autotaxin (ATX, NPP2)

Novel YAP-TEAD Interaction Inhibitor, inhibiting TEAD activity, cell proliferation, and cell migration

Selective and Potent Inhibitor of Fibroblast Activation Protein and Prolyl Oligopeptidase

Novel cathepsin S inhibitor, enhancing oxaliplatin-induced apoptosis through upregulation of Bim expression

Novel irreversible transglutaminase 2 (TG2) inhibitor

Novel tissue transglutaminase (TG2) inhibitor

Appropriate clinical biomarker to recapitulate drug-drug interactions mediated by OATP inhibition

Novel destabilizer of the endosome membrane, enhancing the endosome-leakage activity of cell-penetrating peptides and facilitating the endosomal escape of macromolecules initially internalized by mammalian cells via endocytosis

Water soluble glyburide, inhibitor of the sulfonylurea receptor 1 (SUR1), regulating subunit of the ATP-sensitive potassium channels (KATP) in pancreatic beta cells

Cell-permeable, Irreversible, Non-cytotoxic Pan Caspase Inhibitor

Novel inhibitor of LRRK1, suppressing osteoclast function, but not osteoclast differentiation

Novel inhibitor of the oncoprotein gankyrin, preventing the decrease in p53 protein levels associated with high amounts of gankyrin, restoring p53-dependent transcription and sensitivity to DNA damage

Selective Transient receptor potential vanilloid 4 (TRPV4) antagonist

Novel LMP2 inhibitor as a potential treatment for Alzheimer's disease

Novel PI4K2A inhibitor, decreasing the PI4P pools in Golgi and endosomes

Aba-mimicking agonist, preferentially activating dimeric ABA receptors and possesses ABA-like potency in vivo

Novel Selective, Cell Active Inhibitor of Protein Arginine Methyltransferase 5 (PRMT5)

A selective inhibitor of B-RAF protein kinase carrying V600E mutation

Less active enantiomer of LGH447 (AOB37522)

Novel Inhibitor of Human Cytomegalovirus

Selective NPY-Y2 Receptor Antagonist

Novel G6PD inhibitor

Novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth,

HIV inhibitor, showing selective activity against human RNaseH2

Novel potent and selective Plk1 inhibitor

Novel potent inhibitor of human cathepsin L

A potent and specific inhibitor of the cerebroside synthase

Modulator of Lipid Storage