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Others

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Cat. No. Product Name Field of Application Chemical Structure
DC42605 cjoc42
Novel inhibitor of the oncoprotein gankyrin, preventing the decrease in p53 protein levels associated with high amounts of gankyrin, restoring p53-dependent transcription and sensitivity to DNA damage
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DC42603 GSK205
Selective Transient receptor potential vanilloid 4 (TRPV4) antagonist
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DC42602 DB-310
Novel LMP2 inhibitor as a potential treatment for Alzheimer's disease
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DC42601 NC03
Novel PI4K2A inhibitor, decreasing the PI4P pools in Golgi and endosomes
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DC42599 Quinabactin
Aba-mimicking agonist, preferentially activating dimeric ABA receptors and possesses ABA-like potency in vivo
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DC42598 DC_Y134
Novel Selective, Cell Active Inhibitor of Protein Arginine Methyltransferase 5 (PRMT5)
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DC42597 PLX4032
A selective inhibitor of B-RAF protein kinase carrying V600E mutation
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DC42595 LGH447-(1S,3R,5R)
Less active enantiomer of LGH447 (AOB37522)
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DC42594 MLS8969
Novel Inhibitor of Human Cytomegalovirus
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DC42590 ML075 (SF-11)
Selective NPY-Y2 Receptor Antagonist
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DC42589 CB-83
Novel G6PD inhibitor
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DC42588 UNC10112785
Novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth,
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DC42585 RHI002
HIV inhibitor, showing selective activity against human RNaseH2
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DC42584 CAP-53194
Novel potent and selective Plk1 inhibitor
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DC42582 ML036
Novel potent inhibitor of human cathepsin L
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DC42581 EtDO-P4
A potent and specific inhibitor of the cerebroside synthase
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DC42579 ML206
Modulator of Lipid Storage
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DC42578 (-)-ML206
Less active enantiomer of ML206 (AOB1395), acting as a modulator of lipid storage
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DC42575 HyT36(-Cl) (Deschloro-HyT36)
Control molecule for HyT36 (AOB4848) which is a hydrophobic inducer of the degradation of stabilized proteins
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DC42569 HJ-PI01
Novel Pim-2 inhibitor, inducing apoptosis and autophagic cell death in triple-negative human breast cancer
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DC42567 SC-10
PKC activator, stimulating PKC mediated myosin light chain phosphorylation without activating MLC kinase
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DC42566 Fluzinamide
Antiepileptic anticonvulsant, significantly attenuating after discharge durations and the severity of the accompanying convulsive responses
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DC42565 PF-562271 HCl
Novel focal adhesion kinase (FAK) inhibitor
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DC42564 Pemafibrate sodium
Novel selective PPARalpha modulator (SPPARMalpha), improving dyslipidemia, enhancing reverse cholesterol transport and decreasing inflammation and atherosclerosis
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DC42563 Varespladib Sodium
Selective Phospholipase A2 Inhibitor
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DC42562 Autogramin-2
Novel autophagy inhibitor, selectively targeting cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A), and directly competing with cholesterol binding to the GRAMD1A StART domain
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DC43047 Thunberginol C
DC42547 [Tyr11]-Somatostatin
[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology.
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DC42546 THK5351
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.
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DC42545 Cytidine 5'-diphosphate trisodium salt
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA.
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