Novel highly potent and selective CDK7 inhibitor, demonstrating broad anti-tumor activity in vivo

Novel selective OXE receptor antagonist

Potent differentiating agent

Natural potent alpha-mannosidase inhibitor, exhibiting antimetastatic, antiproliferative, and immunomodulatory activities

Novel clickable tumor-specific irreversible inhibitor of stearoyl CoA desaturase (SCD)

D2 dopamine receptor partial agonist in adenylyl cyclase inhibition assay and antagonist in the GIRK and phospho ERK1/2 assays

Selective D2 dopamine receptor antagonist

Antagonist of the mammalian bile acid sensor farnesoid-X-receptor (FXR)

Potent Inhibitor of Plasmodium FK506 Binding Protein 35 (FKBD35), also act as a HIV inhibitor

5-HT2 antagonist

Novel fibroblast growth factor receptor modulator for treating neurodegenerative diseases

D2 selective dopamine agonist, showing anxiolytic and anti-parkinsonian activities

Novel, potent, selective, and competitive antagonist of LTD4 and LTE4

Peripheral vasodilator

Neuroprotective agent, alleviating stroke-induced neuroinflammation

Novel inhibitor of RhoG-hepcidin uptake

β-Lactam antibiotic against multi-drug resistant pathogens

Antibacterial, inhibiting bacterial folic acid synthesis by competing with para amino benzoic acid

Novel inhibitor of airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease (COPD)

Novel potent inhibitor of osteoclastogenesis, suppressing both equilibrative nucleoside transporters and concentrative nucleoside transporters

Fluorescent substrate which can be hydrolyzed by the proteasome to release free AMC and the fluorescence of which is proportional to the proteasome activity

Natural immunosuppressive agent, effectively blocking T cell proliferation and survival while profoundly inhibiting pro-inflammatory IFNγ and IL-17 production by fully differentiated effector Th1 and Th17 cells, also acting as an estrogen receptor antagon

Novel potent and selective inhibitor of the cellular PDGF receptor kinase and PDGF receptor-induced cell proliferation

Agonist of TRPV1

Sunitinib analog, acting as a potential inhibitor for nucleoside diphosphate kinase (NDK) from Leishmania major (LmNDK)

Potent c-MET inhibitor

Novel potent c-MET inhibitor

Novel dual Inhibitor of repair enzymes 8-oxoguanine DNA glycosylase (OGG1) and human MutT Homolog 1 (NUDT1 or MTH1), increasing sensitivity of tumor cells to oxidative stress

Novel Nonsteroidal Inhibitor of Carbonic Anhydrase IX

Inhibitor of 17β-hydroxysteroid dehydrogenases (17β-HSDs)