Homoorientin is a potent inhibitor of COX-2 with an IC50 value of 39 μM.

Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Thalidomide-O-C7-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based cereblon ligand and a linker used in PROTAC technology.

Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131). Pomalidomide-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

PROTAC BRD4 Degrader-5 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GAL-02-221 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines.

(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG2-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Thalidomide-O-PEG4-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Nanvuranlat (JPH203) is a potent, selective L-type amino acid transporter 1 (LAT1, SLC7A5) inhibitor with IC50 of 60 nM (leucine uptake inhibition), but not LAT2.

Allopole-A-octyl diamine derivative is the prodrug of Allopole-A.

Allopole prodrug moiety is the prodrug form of Allopole.

VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

PAA-38 is a highly potent selective inhibitor targeting bacterial prolyl-tRNA synthetase (ProRS). PAA-38 againsts Pseudomonas aeruginosa ProRS (PaProRS) with a Kd value of 0.399 nM and an IC50 value of 4.97 nM. PAA-38 againsts human cytoplasmic ProRSs (HsProRS) with an IC50 value of 35.5 nM. PAA-38 demonstrates an in vitro antibacterial activity of minimum inhibitory concentration (MIC) = 4-8 μg/mL.

ACA22 is a small molecule KRAS inhibitor, inhibits KRAS-mediated signal transduction in cells expressing wild type (WT) and G12D mutant KRAS.

QCA276 is a novel potent BET proteins inhibitor with IC50/Ki of 10/.3 nM, QCA276 is the BET ligand for PROTAC QCA570.

Nangibotide is a TREM-1 receptor inhibitor that can modulate innate immune response. Nangibotide can reduce systemic and in situ inflammatory reaction in rodent models of myocardial ischaemia‐reperfusion.

Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. Pomalidomide-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

10-SLF is a PROTAC FKBP12 degrader. 10-SLF induces a ternary complex between FKBP12 and FBXW7-R465C, and promotes FBXW7-R465C-dependent proteasomal degradation of FKBP12. 10-SLF selectively reduces FKBP12 levels in cells expressing FBXW7-R465C.

ATO 532 Acid has an identical molecular structure to ATTO 532 Acid. It is a fluorescent label related to the well - known dye Rhodamine 6G. This dye is characterized by strong absorption, a high fluorescence quantum yield, excellent thermal and photostability, and good water solubility. Thanks to these features, ATO 532 is highly appropriate for single - molecule detection applications and high - resolution microscopy techniques, including Photoactivated Localization Microscopy (PALM), direct Stochastic Optical Reconstruction Microscopy (dSTORM), Structured Illumination Microscopy (SIM), and Stimulated Emission Depletion Microscopy (STED). In addition, it is also very suitable for use in Fluorescence - Activated Cell Sorting (FACS) and Fluorescence In Situ Hybridization (FISH). The fluorescence of ATO 532 Acid can be most efficiently excited within the range of 515 - 545 nanometers.

ATO 488 has the same molecular structure as ATTO 488. It is a new type of hydrophilic fluorescent dye that offers excellent water - solubility, strong absorption capacity, a high fluorescence quantum yield, as well as outstanding thermal and photostability. Due to these remarkable properties, ATO 488 is highly suitable for single - molecule detection applications and high - resolution microscopy techniques such as Structured Illumination Microscopy (SIM) and Stimulated Emission Depletion Microscopy (STED). Moreover, this dye is also well - suited for use in Fluorescence - Activated Cell Sorting (FACS) and Fluorescence In Situ Hybridization (FISH).

The ATO 465 molecule shares the same structure as ATTO 465. It is a fluorescent dye derived from the well - known acridone dye. ATO 465 has moderate hydrophilicity. Its fluorescence can be effectively excited within the range of 420 - 465 nm. This dye has remarkable features such as strong absorption, a high fluorescence quantum yield, excellent thermal stability, and high photostability. In an aqueous solution, this dye exhibits an astonishingly large Stokes shift of 55 nm. When it comes to a solid matrix, especially under low - temperature conditions, the dye emits intense and long - lasting phosphorescence.

ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.

The ATO 425 Acid molecule is equivalent to ATTO 425. It is a novel fluorescent marker with a coumarin structure. This marker boasts several notable characteristics, including a high fluorescence quantum yield, excellent photostability, and a relatively low molecular weight.

AF 488 Cadaverine is a carbonyl - reactive structural unit. In the presence of activators like EDC or DCC, or activated esters such as NHS esters, it can be used to modify carboxyl groups through the formation of stable amide bonds. Additionally, it can serve as a polar tracer and an active dye for labeling proteins via carboxylic acid molecules.