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(S,R,S)-AHPC-PEG4-N3

  Cat. No.:  DC67755   Featured
Chemical Structure
1797406-81-5
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More than 5000 active chemicals with high quality for research!
Field of application
(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cas No.: 1797406-81-5
Chemical Name: (S,R,S)-AHPC-PEG4-N3
Synonyms: (S,R,S)-AHPC-PEG4-N3;E3 ligase Ligand-Linker Conjugates 4;(S,R,S)-AHPC-PEG4-Azide;BCP33419;XWC40681;VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4;(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dime
SMILES: S1C=NC(C)=C1C1C=CC(=CC=1)CNC([C@@H]1C[C@H](CN1C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCN=[N+]=[N-])=O)=O)O)=O
Formula: C32H47N7O8S
M.Wt: 689.82
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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